Biochemistry - Kaplan USMLE Step1 Flashcards
What is The product of gene expressions?
Proteins
What is gene expression?
Transcription+ translation
What is the length of transcript DNA?
10^4 - 10^5
What is the time of transcription?
Throughout interphase g1 - s - g2
What is the time of DNA Replication in the cell cycle?
Where is done?
During S phase
Nucleus
What are the tissues in resting phase(G0)?
Nerves
Muscle
Liver
What is the nucleoside?
Examples?
Base + sugar Adenosine Guanosine Cytidine Uridine Deoxythymidin
What is the nucleotide?
Example?
Base + sugar + phosphate AMP GDP CTP ATP UTP dTTP
What are the purine bases of nucleotides?
Adenine
Guanine
What is the differences and similarities of uracil and thymine?
Uracil : RNA, PYRIMIDINE, NO METHYL GROUP
Thymine: DNA, Methyl group, pyrimidine
What is the tumor related with t(9;22)?
What is the name of chromosome and oncogenes?
CML
Philadelphia chromosome
C-abl
What is the tumor related with t(15;17)? And the oncogene?
AML
Retinoid receptor- alfa
What is the tumor related with t(14;18)?
The name of oncogene?
Follicular Lymphoma
Bcl-2
What is the tumor related with t(8;14)? And name of oncogene?
Burkitt lymphoma
C-myc
What are the enzymes in glycolysis that catalyze irreversibly?
Glucokinas/hexokinase
PFK-1
PDH