Biochemistry - Kaplan USMLE Step1 Flashcards

0
Q

What is The product of gene expressions?

A

Proteins

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1
Q

What is gene expression?

A

Transcription+ translation

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2
Q

What is the length of transcript DNA?

A

10^4 - 10^5

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3
Q

What is the time of transcription?

A

Throughout interphase g1 - s - g2

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4
Q

What is the time of DNA Replication in the cell cycle?

Where is done?

A

During S phase

Nucleus

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5
Q

What are the tissues in resting phase(G0)?

A

Nerves
Muscle
Liver

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6
Q

What is the nucleoside?

Examples?

A
Base + sugar 
Adenosine
Guanosine
Cytidine
Uridine
Deoxythymidin
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7
Q

What is the nucleotide?

Example?

A
Base + sugar + phosphate
AMP
GDP
CTP
ATP
UTP
dTTP
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8
Q

What are the purine bases of nucleotides?

A

Adenine

Guanine

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9
Q

What is the differences and similarities of uracil and thymine?

A

Uracil : RNA, PYRIMIDINE, NO METHYL GROUP

Thymine: DNA, Methyl group, pyrimidine

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10
Q

What is the tumor related with t(9;22)?

What is the name of chromosome and oncogenes?

A

CML
Philadelphia chromosome
C-abl

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11
Q

What is the tumor related with t(15;17)? And the oncogene?

A

AML

Retinoid receptor- alfa

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12
Q

What is the tumor related with t(14;18)?

The name of oncogene?

A

Follicular Lymphoma

Bcl-2

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13
Q

What is the tumor related with t(8;14)? And name of oncogene?

A

Burkitt lymphoma

C-myc

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14
Q

What are the enzymes in glycolysis that catalyze irreversibly?

A

Glucokinas/hexokinase
PFK-1
PDH

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15
Q

What are the coenzymes for PDH?

A
Thiamine
CoA
Lipoic acid
FAD
NAD