RAPID REVIEW- Equation review

Question 1

Sensitivity

Answer 1

Sensitivity= TP/ (TP+ FN)

Question 2

Specificity

Answer 2

Specificity= TN/ (TN+FP)

Question 3

Positive predictive value

Answer 3

PPV= TP / (TP + FP)

Question 4

Negative predictive calue

Answer 4

NPV= TN/ (FN+ TN)

Question 5

Odds ratio (for case-control studies)

Answer 5

Odds ratio = ad/ bc

Question 6

Relative risk

Answer 6

Relative risk = a/(a+b)
———-
c/(c+d)

Question 7

Attributable risk

Answer 7

Attributable risk= a c
——– - ———
a+b c+d

Question 8

Number needed to treat

Answer 8

1/ absolute risk reduction

Question 9

Number needed to harm

Answer 9

1/ attributable risk

Question 10

Hardy-Weinberg equilibrium

Answer 10

p2 + 2pq + q2= 1

p+q=1

Question 11

Volume distribution

Answer 11

Vd= amount of drug in the body
——————————————
plasma drug concentration

Question 12

Half-life

Answer 12

t 1/2 = 0.693 x Vd
—————–
CL

Question 13

Drug clearance

Answer 13

CL= rate of elimiation of drug
———————————— = Vd x Ke (elim. constant)
plasma drug concetration

Question 14

Loading dose

Answer 14

LD= Cp x Vd
————
F

Question 15

Maintenance dose

Answer 15

D= Cp x CL x τ
—————-
F

Question 16

Cardiac output

Answer 16

CO = rate of O2 consumption
———————————————————–
arterial O2 content - venous O2 content

CO= stroke volume x heart rate

Question 17

Mean arterial pressure

Answer 17

MAP= cardiac output x total peripheral resistance

MAP= 2/3 diastolic + 1/3 systolic

Question 18

Stroke volume

Answer 18

SV = EDV- ESV

Question 19

Ejection fraction

Answer 19

EF= SV EDV- ESV
—— = —————
EDV EDV

Question 20

Resistance

Answer 20

Resistance= driving pressire (ΔP) 8 n (viscosity)x lenght
—————————– = ——————————-
flow (Q) πr4

Question 21

Net filtration pressure

Answer 21

Pnet= [(Pc- Pi)- (πc- πi)]

Jv= net fluid flow = (Kf)(Pnet)

Question 22

Renal clearance

Answer 22

Cx = UxV/ Px

Question 23

Glomerular filtration rate

Answer 23

GFR= Uinulin x V/Pinulin= Cinulin

GFR= Kf [(PGC - PBS)- (πGC- πBS)]

Question 24

Effective renal plasma flow

Answer 24

ERPF= UPAH x V
——– = CPAH
PPAH

Question 25

Renal blood flow

Answer 25

RBF= RPF
———
1- Hct

Question 26

Filtration Fraction

Answer 26

FF= GFR/RPF

Question 27

Henderson-Hasselbalch equation (for extracellular pH)

Answer 27

[HCO3-]
pH = 6.1 + log ————–
0.03 PCO2

Question 28

Winters formula

Answer 28

PCO2 = 1.5 [HCO3-] +8 +-2

Question 29

Physiologic death space

Answer 29

PaCO2-PECO2
VD= VT x ————————
PaCO2

Question 30

Pulmonary vascular resistance

Answer 30

Ppulm artery- PL atrium
PVR= ————————————-
cardiac output

Question 31

Alveolar gas equation

Answer 31

PaCo2
PAO2 = PIO2 - ————–
R