RANZCOG - HPV vaccine

Question 1

What are the 2 most common oncogenic strains of HPV and what percentage of cervical cancer do they account for?

Answer 1

16 and 18

account for 70%

Question 2

HPV is implicated in which cancers?

Answer 2

• vulval
• vagina
• penis
• anus
• head and neck

Question 3

list the two non oncogenic HPV strains and what they cause?

Answer 3

6 and 11

genital warts

Question 4

What is the HPV made up of and how does it work?

Answer 4

• made up of virus like proteins
• do not contain live or attenuated virus
• induces an antibody response
• if then exposed to HPV body mounts antibodies and protects from infection

Question 5

What does Gardasil 9 protect against?

Answer 5

6, 11, 16, 18, 31, 33, 45, 52, 58

potentially protects against 90% of cervical cancer

Question 6

What is the optimal timing for the Gardasil vaccination?

Answer 6

• ideally given before 15 years of age and before onset of sexual activity