RANITIDINE

Question 1

BRAND NAME

Answer 1

Zantac

Question 2

DRUG CLASS

Answer 2

Histamine H2 antagonists

Question 3

THERAPEUTIC ACTIONS

Answer 3

Inhibits the action of histamine at the H2 receptor site located primarily in gastric parietal cells, resulting in inhibition of gastric acid secretion.

Question 4

INDICATIONS

Answer 4

Maintenance therapy for duodenal and gastric ulcers after healing of active ulcer(s). Management of gastric hypersecretory states (Zollinger-Ellison syndrome). Treatment of and maintenance therapy for erosive esophagitis.
Treatment of gastroesophageal reflux disease (GERD).

Question 5

CONTRAINDICATIONS

Answer 5

Porphyria
Hypersensitivity

Question 6

SIDE EFFECTS

Answer 6

Headache, dizziness.
Rarely hepatitis, thrombocytopaenia, leucopaenia, hypersensitivity, confusion, gynaecomastia, impotence, somnolence, vertigo, hallucinations.

Question 7

NURSING RESPONSIBILITIES

Answer 7

Monitor signs of hypersensitivity reactions, including pulmonary symptoms (tightness in the throat or chest, wheezing, cough, dyspnea) or skin reactions (rash, pruritus, urticaria). Notify physician or nursing staff immediately if these reactions occur.

Be alert for signs of vasculitis, including fatigue, weakness, muscle pain, joint pain, numbness, fever, loss of appetite, and weight loss. Report these signs to the physician.