Random Questions Flashcards

1
Q

What drug can cause blue vision and which drug can cause yellow vision in overdose

A

Blue vision can be cause by slidenafil and yellow vision is a sign of digoxin toxicity alongside nausea and vomiting

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2
Q

What increases the risk of VTE

A
Obesity
Smoking
oral contraceptives
Tamoxifen(anti osterogen uses for up to five years in breast cancer it is a prodrug and interacts with paroxteine SSRI are inhibitors)
35+
First degree relative under 45with history of DVT
Immobilisation
Surgery
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3
Q

What drugs are contraindicated in myasthenia gravis

A

Quinine (also contraindicated in optic neuritis and tinnitus and can cause QT prolongation )
Benzodiazepines
Amingoglyclasides
Antimuscaranics

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4
Q

What drugs can you not put in a MDS

A
Topiramate
Sodium valproate
Nicorandil (mouth ulcers)
Dabigatran (avoid if egfr <30)
Orodispersible tablers or buccal tablers or sublingual tablers
Cytotoxic drugs
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5
Q

Which SGLT is not licensed to be used with pioglitazone for triple therapy

A

Dapagflozin

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6
Q

Which gliptin DPP4 inhibitor is best in renal impairment and which can cause hepatotoxicity and which does not yet have a place in diabetes management

A

Linagliptin can be used in renal impairment
Vildagliptin can cause hepatotoxciith
Alogliptin has no place in diabetes management as of yet (25mg OD or 12.5mg or 6.25 mg in renal impairment

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7
Q

Which drugs can cause benign intracranial hypertension (headaches and visual disturbances) for which you must stop taking the drug

A

Tetracyclines
Lithium
Ciclsporin (moniter potassium and magnesium with this and stop it if antihypertensive drugs do not control a patients hypertension)

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8
Q

What is pyrzanamide contraindicated in ?

A

Acute attacks of gout
Side notes;
Ticagrelor aspirin and thiazides can cause gout
Remember allopurinol or febuxstat are used for prophylaxis only and should not be used in an acute attack of gout as they can precipitate a attack of gout
Prophylactic drugs should be started 1-2 weeks after a gout attack has settled

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9
Q

Dueduonal ulcer versus gastric ulcer

A

Deudanal ulcer is worse after eating and pain is worse at night

Gastric ulcer pain is worse on empty stomach and is relieved by food

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10
Q

Drugs lowering seizure threshold

A

Tramadol
Quinones -e.g. ciprofloaxcin

Isoniazid
Theophylline

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11
Q

Which MR of nifedipine should not be used in GI diseases like IBD as dose form is not appropriate

A

Adalat LA Valni XL

Side note nifedipine can be used for 8 weeks to treat chronic anal fissures
0.2/0.3%
It can also treat premature labour

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12
Q

Which DOAC can be crushed and added to a NG tube if needed

A

Rivaroxaban

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13
Q

What are signs of adrenal insufficiency and what drugs can cause them

A
Fatigue
Anorexia
Nausea 
Vomiting
Hypotension
Hyponatremia
Hyperkalemia
Hypoglycaemia

Ketoconzole MHRA warning only use oral Keto on ole for Cushing syndrome
And measure cortisol , LFTs (Ketoconzaloe if hepatotoxic moniker before starting and weekly for one month )
Do ECG before hand as ketoconazole can prolong QT interval
Prolonged use of steroids can cause adrenal atrophy leading to adrenal insufficiency

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14
Q

Compliance
Adherence
Concordance

A

Compliance is the extent to which a patients behaviour match’s the HCPS recommendations
Adherence is the extent to which a patients behaviour match’s the AGREED HCPs recommendations
Adherence can be intentional or unintentional
Concordance is the process by which a patient and HCP come to a mutual agreement regarding treatment

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15
Q

Contraindications of antimuscarinics

A

GI obstruction
Paralytic ileus (opioids and antispasmodics also contraindicated in paralytic ileus)
Myasthenia gravis
Enlarged prostate
Ullcerative colitis
Toxic megacolon (use of loperamide can cause toxic megacolon in UC therefore avoid )

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16
Q

Paracetamol P GSL etc

OTC for 2month plus

A

Suppositories P
32 pack tablets P
16 pack tablets GSL

Calpol
Lower strength 125/5
100ml GSL 200 ml P

Higher strength 250/5
80 ml GSL 100ml+ P

17
Q

Ibuprofen OTC

From 3 month plus

A

Suspension 100mg/5ml
Pack size 100ml GSL
Pack size 200ml P

Suspension 200mg/5ml
100ml pack P
Pack 16 200 mg GSL
Pack 24 or 96 400mg P

Take with food label on NSAIDS

18
Q

Which SSRI is okay in breast feeding and best one for angina treatment

A

Serteraline

19
Q

Which cephalosporin is associated with skin reactions in children

A

Cefaclor a second generation