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MRCP Part 1 > Random Pharmacology > Flashcards

Random Pharmacology Flashcards

1
Q

Adverse effect of tacrolimus

A

Tremor - worse with outstretched hands

Tolerance - impaired glucose tolerance

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2
Q

Drug causes of gynaecomastia

A

Gay DISCO

  • Goserelin
  • Digoxin
  • Isoniazid
  • Spironolactone*** most common
  • Cimetidie
  • Oestrogen
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3
Q

How does carbamazepine work?

A

Binds to sodium channels, increasing the refractory period

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4
Q

How do triptans work?

A

5HT agonists (B and D)

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5
Q

Triptan contraindications

A

IHD

Cerebrovascular disease

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6
Q

CYP450 inducers

A

ST CRAP GP

Sulfonylureas
Topiramate

Carbamazepine
Rifampicin
Alcohol (chronic)
Phenytoin

Griseofuvlin
Phenobarbitol

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7
Q

CYP450 inhibitors

A

VIDEOCASE

Valproate
isoniazid
Disulfiram
Erythromycin/clarithromycin
Omeprazole
Chloramphenicol/Cimetidine
Allopurinol
Sulfonamide
Ethanol (acute)
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MRCP Part 1 (8 decks)

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