Random Facts Flashcards
Level that structures pass through diaphragm
IVC - T8
Esophagus - T10
Aorta - T12
Alpha 1
G-protein receptor - q (works via IP3-Dag)
^ vascular smooth muscle contraction
Mydriasis (pupillary dialtor muscle contraction)
Urinary retention (intestinal and bladder sphincter contraction)
Increases MAP
Alpha 2
G-protein receptor - i(works by decreasing cAMP) Decreases sympathetic tone Decreases insulin release Inhibits lipolysis Increases platelet aggregation Decreases aqueous humor production
Beta 1
G-protein receptor - S ((increases cAMP)
increases HR, contractility, CO, renin, lipolysis
Beta 2
G-protein receptor- S (increases cAMP)
Vasodilation, bronchodilation, increases lipolysis, insulin release, aqueous humor production, cellular K+ uptake
Beta 3
G-protein receptor - S
increases lipolysis, thermogenesis in skeletal muscle, and bladder relaxation
3 = pee
M1
G-protein receptor - q
mediates higher cognitive function, stimulates enteric NS
M2
G-protein receptor - I
decrease HR and contractility of atria
M3
increases exocrine grand secretion (lacrimal sweat salivary, gastric acid), gut peristalsis, bladder contraction, bronchoconstriction, miosis (pupillary sphincter muscle contraction), ciliary muscle contraction (accomodation), insulin release
D1
G-protein receptor - S
relaxes renal VSM
activates direct path of striatum
D2
G-protein receptor - I
modulate neurotransmitter release in brain
Inhibits indirect pathway of striatum
H1
G-protein receptor -q
increases nasal and bronchial mucus production,increases vascualr permeability, bronchoconstriction, pruritus, pain
H2
G-protein receptor- S
increases gastric acid secretion
V1
G-protein receptor - q
increases vascular smooth muscle contraction
V2
G-protein receptor - S
increases H2O permeability and reabsorption by upregulating aquaporin 2 channels in collecting tubules
