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RUSVM Virology > Random Exam 2 Questions > Flashcards

Random Exam 2 Questions Flashcards

1
Q

T/F: Infectious laryngotracheitis infects turkeys

A

False

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2
Q

T/F: Foals infected with EHV-1 present with interstitial pneumonia systemic disease and high case fatality rate

A

True

Equine Abortion Virus

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3
Q

T/F: Most EHV-1 abortions usually occur between 3-5 months of gestation in mares

A

False

Occur in last trimester (between 8th & 10th month)

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4
Q

What is the incubation period for pseudorabies in swine?

A

~30 hours

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5
Q

T/F: Pseudorabies in adult pigs is characterized by intense pruritis, ganglioneuritis, and high mortality rate

A

False

Pigs don’t get pruritus with pseudorabies, only secondary hosts

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6
Q

T/F: Valtrex cannot be used to treat a herpesvirus infection caused by a herpesvirus with mutation in its thymidine kinase gene

A

True

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7
Q

T/F: Mortality in chickens presenting with infectious laryngotracheitis is usually due to occlusion of the trachea by a caseous plug.

A

True

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8
Q

T/F: A characteristic of infectious bovine rhinotracheitis is that the severity of the respiratory form is largely determined by the extent of secondary bacterial infection.

A

True

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9
Q

T/F: The hemadsorption-inhibition assay is always carried out using virus infected cell culture.

A

True

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10
Q

T/F: Keratitis describes inflammation of the keratin layer of the epidermis

A

False

Inflammation of the cornea

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11
Q

T/F: Papillomavirus infections are characterized by proliferative growth of infected cells.

A

True

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12
Q

T/F: Two forms of fowlpox have been described in chickens; a cutaneous form and a diphtheritic form

A

True

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13
Q

T/F: Newborn puppies infected with canine parvovirus may manifest myocarditis and cerebellar hypoplasia

A

False

No cerebellar hypoplasia

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14
Q

T/F: Fowlpox is mechanically transmitted by mosquitoes and lice

A

True

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15
Q

T/F: Azidothymidine [AZT], an antiviral drug, inhibits replication of feline immunodeficiency virus by inactivating the viral enzyme that cleaves polyproteins into functional proteins.

A

True

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16
Q

T/F: Porcine parvovirus infection in pigs is a persistent infection that results in continuous contamination of the environment

A

True

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17
Q

T/F: Infectious bovine rhinotracheitis is also referred to as “red nose”

A

True

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18
Q

T/F: Hemorrhagic disease of puppies is also known as “fading puppy syndrome”

A

True

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19
Q

T/F: Mortality in the wet form of fowlpox is due to asphyxiation brought on by occlusion of the larynx

A

True

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20
Q

T/F: Milker’s nodule is a condition observed in persons infected with the virus that causes pseudorabies

A

False

Pseudocowpox, not pseudorabies

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21
Q

T/F: African swine fever is exotic in the United States

A

True

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22
Q

T/F: Alphaherpesviruses multiply optimally at low body temperature, establish latent infections in nerve ganglia, and infected cells show cytomegaly

A

False

no cytomegaly

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23
Q

T/F: Poxviruses that belong to the same genus usually show antigenic cross-reactivity.

A

True

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24
Q

T/F: Canine parvovirus diarrhea results from virus replication in the mature enterocytes of the intestinal tract

A

False

Immature enterocytes

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25
Q

T/F: In contrast to parvoviruses that infect other domestic species, porcine parvovirus tends to cause persistent infections with chronic shedding of the virus

A

True

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26
Q

T/F: In North America, sheep are the main reservoirs in the transmission of malignant catarrhal fever

A

True

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27
Q

T/F: A carrier animal sheds virus only intermittently

A

False

Could be continuous or intermittent

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28
Q

T/F: Papillomavirus infection of the skin begins with virus multiplication in the keratinized layer of the epidermis

A

True

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29
Q

T/F: Type I and II interferons enhance cellular expression of MHC class I proteins.

A

True

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30
Q

T/F: Viruses are readily demonstrated using bright-field light microscopy

A

False

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31
Q

T/F: African swine fever is mechanically transmitted by soft ticks

A

False

[Biological, not mechanical]

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32
Q

T/F: Aplastic anemia in chickens due to Chicken Infectious Anemia is caused by direct infection of the RBC precursor stem cells

A

True

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33
Q

T/F: Canine parvovirus is a mutant strain of feline parvovirus

A

False

34
Q

T/F: Persitent infection with intermittent or continuous viral shedding occurs in all herpesvirus infections

A

False

Some are just localized inflammation reactions

35
Q

T/F: Herpesviruses that lack the thymidine kinase gene are resistant to the antiviral drug acyclovir

A

True

36
Q

T/F: Infectious laryngotracheitits has not been reported in turkeys

A

True

37
Q

T/F: Recovered adult pigs serve as the main reservoirs of the virus that causes pseudorabies

A

True

38
Q

T/F: Cross neutralization and cross protection occur among the subgroups of feline leukemia virus

A

False

Subgroup specific

39
Q

T/F: Feline parvovirus is antigenically related to canine parvovirus 2

A

True

40
Q

The Coggins test is used in detecting horses with:

A

Equine infectious anemia

41
Q

An incorrect statement concerning equine infectious anemia is

  • The virus is transmitted by blood-sucking insects
  • Preventative measures include vaccination
  • The virus may cross the placenta and infect the fetus
  • Animals that survive infection serve as carriers throughout their lives
A

Preventative measures include vaccination

42
Q

Each disease is paired with a host. Which pair is mismatched?

  • Cowpox - cat
  • Postweaning multisystemic wasting syndrome - cattle
  • Infectious laryngotracheitis- c hicken
  • Pseudorabies - horse
A

Postweaning multisystemic wasting syndrome is in PIGS

43
Q

Encephalitis is one of the manifestations of the diseases listed below except

  • Goatpox
  • Equine herpesvirus-1 disease
  • Infectious canine hepatitis
  • Pseudorabies
A

Goatpox

44
Q

Viremia is a hallmark of which poxvirus disease?

  • Sheeppox
  • Pseudocowpox
  • Contagious ecthyma
  • Fowlpox
A

Sheeppox

45
Q

Each disease is paired with a reservoir. Which pair is mismatched?

  • Cowpox - rodent
  • Pseudorabies - cattle
  • Feline rhinotracheitis - cat
  • Malignant catarrhal fever - wildebeest
A

Pseudorabies is in pigs, not cattle

46
Q

In North America, which disease is NOT a reportable disease?

  • Pseudorabies
  • Sheeppox
  • Pseudocowpox
  • African Swine Fever
A

Pseudocowpox

47
Q

Regarding pseudorabies, which statement is inaccurate?

  • Infected swine usually present with severe pruritus
  • The disease in invariably fatal in dogs, cats and cattle.
  • The disease is caused by a virus generally regarded as fragile
  • Mortality is due to respiratory failure.
A

Infected swine usually present with severe pruritus

***Only secondary hosts have intense pruritus***

48
Q

Which of the following pairs is mismatched?

  • Adenovirus - carrier state
  • Inclusion body rhinitis - cytomegaly
  • Ulcerative dermatosis - venereal transmission
  • Cowpox - milker’s nodule
A

Milker’s nodule is caused by pseudocowpox, not cowpox

49
Q

Humans are susceptible to which disease?

  • African swine fever
  • Contagious ecthyma
  • Pseudorabies
  • Feline immunodeficiency disease
A

Contagious ecthyma

50
Q

Each disease is matched with a host. Which is mismatched?

  • SMEDI - horses
  • Pseudorabies - cats
  • Infectious laryngotracheitis - chickens
  • Rubarth’s disease - dogs
A

SMEDI is in SWINE ONLY

51
Q

A virus that cannot multiply in nondividing cells

  • Poxvirus
  • Parvovirus
  • Herpesvirus
  • Papillomavirus
A

Parvovirus

52
Q

A virus that transforms T lymphocytes

  • Porcine cytomegalovirus
  • Porcine herpesvirus 1
  • Gallid herpesvirus 2
  • Feline herpesvirus 1
A

Gallid herpesvirus 2

Gallid herpesvirus 2 = Marek’s disease

53
Q

Which of the following conditions has NOT been associated with parvovirus infection in puppies?

  • Enteritis
  • Panleukopenia
  • Cerebellar hypoplasia
  • Myocarditis
A

Cerebellar hypoplasia

(only seen in kitty parvo)

54
Q

Which virus is associated with equine sarcoids?

  • Bovine papillomavirus 1
  • Bovine papillomavirus 3
  • Bovine papillomavirus 5
  • Bovine papillomavirus 4
A

Bovine papillomavirus 1

55
Q

Which poxvirus disease is accompanied by a high mortality rate?

  • Ulcerative dermatosis
  • Contagious ecthyma
  • Lumpy skin disease
  • Sheeppox
A

Sheeppox

56
Q

Concerning Marek’s disease, which statement is inaccurate?

  • Chickens and turkeys are the natural hosts for the virus
  • The most widely used vaccine for disease control consists of an avirulent turkey herpesvirus
  • Infection usually occurs via inhalation of dander from feather follicles
  • Enlarged nerves with loss of striations is one of the more consistant findings in affected birds
A

Chickens and turkeys are the natural hosts for the virus

**Not Turkeys!!**

57
Q

Which genus of Poxviridae produces a hemagglutinin?

A

orthopoxviruses

58
Q

Which genus of Poxviridae does not replicate in embryonated eggs?

A

parapoxviruses

59
Q

Inclusion bodies associated with Fowlpox are called:

A

Bollinger bodies

60
Q

Alpha-herpesviruses grow more efficiently at higher body temperatures

A

No! Other way around, fool!

61
Q

Abortions are commonly seen associated with the genital form of Infectious Bovine Rhinotracheitis

A

False.

Abortions are seen with the respiratory form, which is retarded

62
Q

Aujeszky’s disease or “Mad Itch” are associated with which disease?

A

Pseudorabies

63
Q

Which herpesvirus is associated with “abortion storm”?

A

Equine herpesvirus 1 (Equine Abortion Virus; EHV-1)

64
Q

T/F: “Fading Puppy Syndrome” most commonly occurs in puppies 6 weeks and younger

A

False.

“Fading Puppy Syndrome” (Hemorrhagic Disease of Puppies; Canine herpesvirus 1) most commonly occurs in puppies under 4 weeks of age

65
Q

T/F: Abortions associated with Feline Rhinotracheitis are a result of viremia

A

False.

There is no viremia with Feline Rhinotracheitis. Abortions are typically a result of persistent fever and dehydration

66
Q

T/F: Most papillomaviruses are non-host specific

A

False

67
Q

T/F: The antiviral drug Retrovir® is described as a prodrug and a nucleoside analog of thymidine triphosphate

A

True

68
Q

Interferon-α and Interferon-β bind to the same cell surface receptor and also have identical functions

A

True

69
Q

The synthetic herpesvirus prodrug acyclovir is an analog of which DNA base:

A

Guanosine

70
Q

True or False:
Parvoviruses contain double-stranded DNA, replicate in growing cells, and infect a narrow range of species

A

False

Single-stranded DNA

71
Q

True or False:
Acyclovir requires the host-specified enzyme thymidine kinase to phosphorylate it to acyclovir monophosphate

A

False

Thymidine kinase is a herpesvirus-specified enzyme, not a host-specified enzyme

72
Q

Name three heavy metal salts utilized in negative staining electron microscopy:

A
  1. Sodium phosphotungstate
  2. Osmium tetroxide
  3. Uranyl acetate
73
Q

Most poxviruses are brick shaped.

What is the exception to this rule?

A

Parapoxviruses are ovoid shaped

74
Q

If, as scabs fall off of your cattle, you notice a dark red horseshoe-shaped ring of small scabs surrounding small, wart-like granulomas, what disease should be high on your differential list?

A

Pseudocowpox

75
Q

Which form of sheeppox is more common in lambs and susceptible non-native breeds?

A

Malignant form

76
Q

Which form of Fowlpow has higher mortality: the cutaneous form or diphtheritic form?

A

Wet form [Diphtheritic form]

Death results from suffocation by occlusion of the larynx. Mortality can be up to 50%

77
Q

What is the disease transmitted by Hematopinus suis?

A

Swinepox

78
Q

T/F: Zovirax® is administered as a prodrug

A

True

Zovirax is a trade name for Acyclovir, and is administered as a prodrug. Must be converted by three kinases

79
Q

Cerebellar hypoplasia is characteristic of which disease?

  • A. Feline rhinotracheitis
  • B. Feline panleukopenia
  • C. Hemorrhagic disease of puppies
  • D. Pseudorabies
A

B. Feline panleukopenia

80
Q

T/F: There is no vaccine for the very virulent plus form of Marek’s disease

A

True

81
Q

T/F: Cattle have the cell-free virus in Malignant Catarrhal Fever

A

False

Cattle have the cell-associated virus

RUSVM Virology (4 decks)

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