Random drug reactions Flashcards
what drugs can cause coronary vasospasm?
cocaine, sumatriptan, ergot alkaloids.
What drugs cause cutaneous flushing?
vancomycin, adenosine, niacin, and calcium channel blockers
what drugs can cause torsades de pointes
class III drugs and class IA drugs, macrolides, antipsychotics, and TCAs
What drugs cause hot flashes?
tamoxifen, clomiphene (a selective estrogen receptor modifier used to induce ovulation in tx of infertility)
What drugs cause hyperglycemia?
tacrolimus, protease inhibitors, niacin, HCTZ, beta blockers, and corticosteroids
What drugs can cause hypothyroidism?
lithium, amiodarone, sulfonamides
What drug can cause acute cholestatic hepatitis and jaundice
erythromycin
What drugs cause significant diarrhea?
metformin, erythromycin, colchicine, orlistate, acarbose
What drugs can cause focal to massive hepatic necrosis?
halothane, Amanita phalloides (death cap mushroom- toxin alpha amanitin inhibits RNA pol II, which makes mRNA), valproic acid, acetminophen
What drugs can cause pancreatitis?
didanosine, corticosteroids, alcohol, valproic acid, azathioprine, and diuretics
Drugs that cause agranulocytosis
dapsone, clozapine, carbamezipine, chochicine, methimazole, propylthiouracil (these last two treat hyperthyroidism)
What drugs can cause aplastic anemia?
carbamazepine, methimazole, NSAIDs, benzene, chloramphenicol, propylthiouracil
What drugs cause direct coombs-positive hemolytic anemia?
methyldopa, penicillin
What drugs cause hemolysis in G6PD deficient people?
INH, sulfonamides, dapsone, primaquine, aspirin, ibuprofen, nitrofurantoin
What drugs cause megaloblastic anemia?
phenytoin, methotrexate, sulfa drugs
