Random Cancer lecture at end

Question 1

Anti-Emetics

Answer 1

Anti-Serotonin rec3 = Zofran, ondansetron, dolasetron, ganisetron

Anti-NK1 = Aprepitant

Question 2

Vomiting in Cisplatin

Answer 2

Biphasic

First phase within 24 hours and second phase within 2-4 days (use with Aprepitant)

Any vomiting after 5 days not from treatment!

Question 3

How do you treat emesis once its begun?

Answer 3

Prochloroperazine
STeroids
Hydration

Question 4

Drugs to treat anorexia in cancer

Answer 4

Megesterol Acetate
Pro-motility agents = Reglan and Metoclopropamide
Marinol (THC)

Question 5

Neutropenic Fever

Answer 5

PMN 100.4

Treatment with antibiotics and GSF/GMCSF

Question 6

Hypercalcemia and treatment

Answer 6

from hematogenous cancers, breast cancer, myeloma OR paraneoplastic from PTHRP

Treatment - Fluid, bisphosponate, calcitonin, and watch for arrhythmias!

Question 7

Hyponatremia

Answer 7

<135 serum sodium

cancer and mental status changes

can die from increased ICP

Question 8

Tumor lysis syndrome

Answer 8

release of cell components from NHL/Acute Leukemia and SLCL and leads to Renal Failure, Hypercalcemia, Death

Treatment - Alkalize urine, allopurinol + Rasburicase, Kayexelate, Hydration and watch electrolytes

Question 9

Spinal Compression syndrome

Answer 9

New onset backpain in cancer thats worse with cough and valsalva. Can awakens ppl up at night. can have or not have neuro symptoms.

weakness/ataxia/dysautonomia

MRI Spine and then either radiate lesion or surgery