Random antibodies + tests

Question 1

Anti-mitochondrial antibody

Answer 1

Primary biliary cirrhosis

Question 2

p-ANCA

Answer 2

Ulcerative colitis

Question 3

Ham test

Answer 3

Paroxysmal nocturnal hemoglobinuria

Question 4

anti-GAD

Answer 4

T1DM

Question 5

anti-smooth muscle antibody

Answer 5

autoimmune hepatitis

Question 6

Osmotic fragility test

Answer 6

hereditary spherocytosis

Question 7

anti-endomysial antibodies

Answer 7

coeliac disease

Question 8

anti-scl70 antibody

Answer 8

Diffuse scleroderma

Question 9

anti-dsDNA antibodies

Answer 9

SLE

Question 10

c-ANCA

Answer 10

wegener’s granulomatosis

Question 11

Anti-Ro

Answer 11

Sjogren’s
SLE
Mixed CTD

Question 12

Anti-nuclear

Answer 12

Connective tissue disease (includes anti-dsDNA)

Question 13

Anti-mitochondrial

Answer 13

Primary Biliary Cirrhosis

Question 14

anti-PCD

Answer 14

Esp SCLC

Question 15

anti-CCP

Answer 15

Rheumatoid arhtritis

Question 16

Anti-Acetylcholine receptor

Answer 16

Myasthenia gravis

Question 17

anti-TTG

Answer 17

Coeliac

Question 18

Anti-endomysial antibody

Answer 18

Coeliac, Dermatitis Herpetiformis

Question 19

anti-smooth muscle antibodies

Answer 19

Autoimmune hepatitis

Question 20

cANCA

Answer 20

Wegener’s granulomatosis

Question 21

pANCA - name 2

Answer 21

1. Churg Strauss

2. Microscopic Polyangitis

Question 22

anti-GBM

Answer 22

Goodpasture’s

Question 23

Anti-intrinsic factor

Answer 23

Pernicious anaemia

Question 24

anti-sm antibody

Answer 24

SLE

Question 25

anti-phospholipid antibody

Answer 25

anti-phospholipid syndrome...

Question 26

anti-cardiolipin antibody

Answer 26

Anti-phospholipid syndrome

Question 27

Heterophiles antibody

Answer 27

Infectious mononucleosis

Question 28

Anti-microsomal antibody

Answer 28

Hashimoto's thyroiditis

Question 29

Anti-TPO antibody

Answer 29

Hashimoto's thyroiditis

Question 30

TSH receptor antibody

Answer 30

Grave's disease

Question 31

Anti-Jo1 antibody

Answer 31

Dermatomyositis

Question 32

DNA topoisomerase I antibody

Answer 32

Diffuse scleroderma

Question 33

Anti-centromere antibody

Answer 33

CREST syndrome

Question 34

anti-ribonucleoprotein antibody

Answer 34

Mixed CTD | SLE

Question 35

Anti-platelet antibody

Answer 35

ITP

Question 36

antibodies vs GpIIb-IIIa

Answer 36

autoimmune thrombocytopenia purpura

Question 37

Cells important in T1DM

Answer 37

CD8+ T cells attack beta cells

Question 38

What happens in sensitisation (before full blown anaphylaxis)

Answer 38

Ag recognised by CD4 + Th2 cells and they release IL4 and IL13 This stimulates B cells to make IgE

Question 39

Multiple sclerosis - important antigens?

Answer 39

Myelin basic protein + proteolipid protein

Question 40

Polyarteritis nodosa is associated with which virus in 30% of cases

Answer 40

Hep B

Question 41

Patch testing

Answer 41

Contact dermatitis

Question 42

Latex fixation test

Answer 42

Rheumatoid factor