Microbio- zoonoses + prion disease Flashcards
Definition of zoonoses?
Infections acquired from vertebrate animals
3 infections from rats?
Rabies, plague, Hantan viruses
5 infections from cats
Bartonellosis, Salmonella, Rabies, Q-fever, Toxoplasmosis
5 infections from dogs
Hydatid disease, salmonella, rabies, leptospirosis, ringworm
Small ruminants - 3 infections?
Brucellosis, anthrax, Listeria
5 infections from cattle?
Toxoplasmosis, bovine TB, E coli 0157, anthrax, brucellosis
4 infections from birds
Psittacosis
Influenza A
West Nile virus
cryptococcus
3 infections - Water sports associated
Leptospirosis
Hep A
Giardia
Brucella - what kinda bacteria is it? How is ti transmitted? Which animals?
Gram -ve aerobic bacilli
Facultative intracellular
Transmitted by consumption of untreated dairy.
RUMINANTS + PIGS
Undulant fever, spinal tenderness, lymphadenopathy, hepatosplenomegaly +consumption of shit dairy
Brucellosis
Serology results +ve for brucellosis?
anti-O-polysaccharide antibody
Treatment of brucellosis
Tetracycline or doxycycline, combined with streptomycin
Negri bodies
Rabies
Rabies - serology? Treatment?
ELISA for specific IgM, or RT-PCR
Rabies IgG post-exposure
Plague - what is the bacteria involved?
How is it transmitted?
Bacteria = Yersinia Pestis
In rats, transmitted by fleas
Ingestion of unpasteurised milk –> fever which comes and goes + back pain.
Dx? Ix? Tx?
Dx: Brucellosis
Ix: - anti-O-polysaccharide antibody
Tx: - Tetracycline + streptomycin
Which zoonosis is excreted in dog/rat urine?
Leptospirosis
Painless round black lesions + rim of oedema
Cutaneous anthrax
Rash seen in Lyme disease?
Erythema chronicum migrans
Lyme disease: early stage of illness? Late stage of illness?
Early stage: flu-like, nerve palsies, arthritis, carditis
Late stage: encephalopathy, arthritis
Tx of lyme disease?
2-3 weeks of doxy
4 types of leishmania disease?
Cutaneous
Diffuse cutaenous
Visceral (Kala-Azar)
Mucocutaneous
Diff between lesions seen in diffuse cutaneous vs mucocutaneous leishmaniasis
Diffuse cutaneous: NO ULCERS
Mucocutaneous: ulcers in mouth/nose (mucus membranes)
Vector of leishmaniasis?
Sandfly