RANDOM Flashcards
atopic dermatis is,,,,,,
(3 words)
inflammation of skin
3 specific things pointing to genetic basis of AD
mutation in fillagrin (responsible for skin barrier)
family history of ATOPY (increased IGE response - tend to have allergic reactions)
mutation in CARD11 gene (supports lymphocytes)
crp is a ___ ___ ___
acute phase reactant
primary target of RA
synovial membrane
RA starts as ____ injury
cellular
3 phases:
initiation
amplification
chronic inflammatory
are these phase in RA or OA
RA
in RA, _______ (what cells) proliferate
synoviocytes
in RA, the bone may be eroded by….
granulation tissue
explain how RA affects the blood
anemia
normal RBC
low WBC
increased platelets
3 CV related things that RA does
atherosclerosis
myocardial infarction
stroke
2 ways RA affects lungs
lung fibrosis
caplan’s syndrome (inflammation and scarring of the lungs)
analgesic induced nephropathy/nephrotic syndrome
which class of drug is this unique to
NSAIDS - high dose, chronic use
hypophosphatemia
side effect unique to….
acetaminophen
increased Uric Acid
side effect unique to…..
methotrexate
hypokalemic metabolic alkalosis
side effect unique to…..
corticosteroids
decreased hemoglobin and hematocrit, thrombocytopenia
side effect unique to…..
NSAIDS
GI bleeding in alcoholic patient
side effect unique to….
acetaminophen