Random Flashcards
Blood volume for term infant and preterm infant
term: 80-85 ml/kg
preterm: 100 ml/kg
A double volume exchange results in removal of ____ of the neonates RBCs.
85%
purpura fulminans
complete absence of Protein C or S
(also factor V leiden could)
EXtrinsic pathway + test
PT
*only factor 7 is unique to EXtrinsic
tissue factor + factor 7 (converge at 10)
Intrinsic pathway + test
PTT
12, 11, 9, 8 (converge at 10)
elevated PT and PTT
Congenital deficiency: Factor 1, 2, 5, 10
Acquired deficiency of vitamin K dependent factors 10, 9, 7, 2
elevated PT (nml PTT)
Factor 7 (? doesn’t cause bleeding)
elevated PTT (nml PT)
- corrects with adding nml plasma
8, 9, 11, 12, (vWF- carrier protein for factor 8)
8 = hemophilia A
9 = hemophilia B (“Christmas disease”)
11 = hemophilia C
elevated PTT (nml PT)
*Does NOT correct with adding nml plasma
circulating factor inhibitor
(lupus anticoagulant, heparin contamination)
no air below the stomach bubble
multiple blisters on arms and legs
epidermolysis bulls lethalis
(genetic a/w pyloric atresia and EB lethalis)
Type of craniosynostosis that requires correction to prevent neurologic sequelae
Frontal plagiocephaly - unilateral CORONAL suture
—->a/w Crouton and Apert
(or multiple sutures)
selective neuronal necrosis
- MC pattern of cerebral injury in ________
- clinical outcome: ________
HIE
mental deficiency
seizures, ataxia
feeding difficulties
pyramidal CP
CP type:
mixed tone in same muscle
hearing deficits
speech abnormalities
Athetoid aka
Extrapyramidal aka
Dyskenetic
22q11 deletion most likely to have which CHD:
VSD
Interrupted Arch
ASD
Interrupted arch
Cornelia de lange heart defect
ASD
