Random Flashcards
Enfortumab dosing and moa
1.25 mg/kg max 125 mg day 1 and 8 q3weeks
ADC against nectin 4. MMAE is the payload
High counts on chemo with no gcsf us called?
Leukoerythroblastic reaction
Cinv
HEC > 90%
MEC 30 - 90%
LEC 10 - 30%
minimal < 10%
CINV risk factors (7)
Hist uncontrolled CINV
Hist motion sickness
N/V in pregnancy
Female
<55 years old
Low/non drinker
Hist of GAD
Extravasation
Hot and cold CI
Doxo heat CI
Vinca cold CI
Dexrazoxane for extravasation
1000 mg/m2 days 1 and 2 500 mg/m2 day 3
Max bsa 2
50% dose for crcl < 40
Eligrad dose freq route
7.5 mg subcutaneous q month
Available in 1 3 4 and 6 month injection 7.5 22.5 30 and 45 mg
Bleomycin premeds
Tylenol
Three chemo before platinum at hf
Gem taxol and etoposide
Tisotumab dose freq moa
2mg/kg max 200 q3weeks
ADC with MMAE for TF tissue factor
NTRK positive tumors get which meds
Larotrectinib or entrectinib
Brand name for loncastuximab
Zynlonta
Zylonta dosing
0.15 mg/kg q 3 weeks x 2 doses then 0.075 mg/kg q 3 weeks.
BMI > 35 use manufactured adjusted body weight formula
Libtayo
Cemiplimab
Yervoy
Ipi