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Question 1

Enfortumab dosing and moa

Answer 1

1.25 mg/kg max 125 mg day 1 and 8 q3weeks
ADC against nectin 4. MMAE is the payload

Question 2

High counts on chemo with no gcsf us called?

Answer 2

Leukoerythroblastic reaction

Question 3

Cinv

Answer 3

HEC > 90%
MEC 30 - 90%
LEC 10 - 30%
minimal < 10%

Question 4

CINV risk factors (7)

Answer 4

Hist uncontrolled CINV
Hist motion sickness
N/V in pregnancy
Female
<55 years old
Low/non drinker
Hist of GAD

Question 5

Extravasation
Hot and cold CI

Answer 5

Doxo heat CI
Vinca cold CI

Question 6

Dexrazoxane for extravasation

Answer 6

1000 mg/m2 days 1 and 2 500 mg/m2 day 3
Max bsa 2
50% dose for crcl < 40

Question 7

Eligrad dose freq route

Answer 7

7.5 mg subcutaneous q month
Available in 1 3 4 and 6 month injection 7.5 22.5 30 and 45 mg

Question 8

Bleomycin premeds

Answer 8

Tylenol

Question 9

Three chemo before platinum at hf

Answer 9

Gem taxol and etoposide

Question 10

Tisotumab dose freq moa

Answer 10

2mg/kg max 200 q3weeks
ADC with MMAE for TF tissue factor

Question 11

NTRK positive tumors get which meds

Answer 11

Larotrectinib or entrectinib

Question 12

Brand name for loncastuximab

Answer 12

Zynlonta

Question 13

Zylonta dosing

Answer 13

0.15 mg/kg q 3 weeks x 2 doses then 0.075 mg/kg q 3 weeks.
BMI > 35 use manufactured adjusted body weight formula

Question 14

Libtayo

Answer 14

Cemiplimab

Question 15

Yervoy

Answer 15

Ipi

Question 16

Belrapzo

Answer 16

Benda

Question 17

Trodelvy

Answer 17

Sacituzumab

Question 18

Zepzelca

Answer 18

Lurbinectedin

Question 19

Adcetris

Answer 19

Brentuximab

Question 20

Padcev

Answer 20

Enfortumab

Question 21

Empliciti

Answer 21

Elotuzumab

Question 22

Elotuzumab dosing

Answer 22

10 mg/kg weekly x 8/9 weeks then 20 mg/kg q4 weeks

Question 23

Selinexor

Answer 23

Xpovio