Ovarian Flashcards
1
Q
% of pt with BRCA mutation
A
10 -15%
2
Q
4 classifications of ovarian by tissue or cell type and %
A
Serous 70
Mucinous 3
Endometrioid 10
Clear cell 10 poor prognosis
3
Q
Debulking optimal vs suboptimal
A
Optimal <= 1 cm residual disease
Suboptimal > 1 cm rd
4
Q
HRD stands for
A
Homologous recombination deficiency
5
Q
Which has earlier onset for malignancy BRCA 1 or 2
A
1
6
Q
What stage ovarian gets observation only?
A
Stage 1A or 1B grade 1 endometrioid or low grade serous
7
Q
Stage 1 ovarian regimens for patients less than 70
A
Taxol 175 carbo 5-6
Docetaxel 60 -75 carbo 5-6
Doxil 30 and carbo 5
8
Q
Stage 1 ovarian for patients older than 70
A
Taxol 135 and carbo 5
Taxol 60 and carbo 2 days 1 8 and 15 q 3 weeks
9
Q
Who gets IP
A
IP chemo for stage 2 to 3 with optimal debulking
