Radiosensitivity and characteristics of cell types Flashcards
What are the 5 cell types
VIM, DIM, Multipotential connective tissue, RPM, FPM
What does VIM stand for and what is it
vegatative intermitotic cells
- These are rapidly dividing, undifferentiated with a short lifetime. Most sensitive cells
What does DIM stand for and what is it
Differentiated intermitotic cells
- These are produced by the division of VIM cells, they are actively mitotic but less sensitive than VIM cells
What are multipotential connective tissue cells
These cells divide irregularly, are more differentiated, and are medium radiosensitive
What does RPM stand for and what is it
Reverting post-mitotic cells
- these do not usually undergo mitosis but are capable of cell division, they live long and are more differentiated than the previous cell types and more radioresistant
What does FPM stand for and what is it
Fixed post-mitotic cells
- These do not divide and are highly differentiated thus the most radioresistant
What is an example of each (VIM, DIM, Multiconnective tissue, RPM, FPM)
VIM = Type A spermatogonia
DIM = Intermediate spermatogonia
Multiconnective tissue = endothelial cells, fibroblasts
RPM = Parenchymal cells of liver
FPM = Nerve or muscle cells