Radiosensitivity and characteristics of cell types Flashcards

1
Q

What are the 5 cell types

A

VIM, DIM, Multipotential connective tissue, RPM, FPM

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2
Q

What does VIM stand for and what is it

A

vegatative intermitotic cells
- These are rapidly dividing, undifferentiated with a short lifetime. Most sensitive cells

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3
Q

What does DIM stand for and what is it

A

Differentiated intermitotic cells
- These are produced by the division of VIM cells, they are actively mitotic but less sensitive than VIM cells

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4
Q

What are multipotential connective tissue cells

A

These cells divide irregularly, are more differentiated, and are medium radiosensitive

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5
Q

What does RPM stand for and what is it

A

Reverting post-mitotic cells
- these do not usually undergo mitosis but are capable of cell division, they live long and are more differentiated than the previous cell types and more radioresistant

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6
Q

What does FPM stand for and what is it

A

Fixed post-mitotic cells
- These do not divide and are highly differentiated thus the most radioresistant

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7
Q

What is an example of each (VIM, DIM, Multiconnective tissue, RPM, FPM)

A

VIM = Type A spermatogonia
DIM = Intermediate spermatogonia
Multiconnective tissue = endothelial cells, fibroblasts
RPM = Parenchymal cells of liver
FPM = Nerve or muscle cells

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