Radionuclide Production and Generators Flashcards
Alpha Decay
Occurs in Heavy nuclei; The atomic number 9Z) is reduced by 2 and the mass (a) is reduced by 4
Beta Decay
It occurs in neutron-rich nuclei; The atomic number (Z) of the daughter is one more than the parent; the Mass number (A) is not changed.
Positron Decay
Occurs in proton-rich nuclei; proton converted to a neutron; The atomic number (Z) of the daughter is one less than the parent; the mass number (A) is not changed.
Electron Capture
Positron alternative; electron is “captured” by the nucleus from an orbital shell and combines with a proton to form a neutron.
Atomic Number (Z) of the daughter is one less than the parent. Mass number (A) does not change.
Isomeric Transition
Daughter nuclide may still exist in excited state and have excess energy to dispel after beta, positron or electron capture. Excess can be gamma rays.
Radionuclide production methods
Fission (in a reactor)
(n,f); neutron-Inititated
produces 2 “daughters” + more neutron + heat;
Neutron Capture (in a reactor)
(n, y)
Thermal neutron capture—–radioactive isotope of parent that decay by beta emission
Fast neutron——-Transmutation
Cyclotron
Charged particles accelerated in “dees”, bombard target material
variety of products possible.
Nuclear Fission
Requires heavy nuclei
Neutron accelerated at nucleus at high speed, nucleus breaks into 2 or more pieces, this releases an extreme amount of heat (heat used by nuclear power)
Some piece broken down into Mo-99, I-131, Xe-133
Neutron Capture
another nucleus captures alternative to fission neutron released during fission; excited nucleus that decays by gamma ray emission.
Global production of Mo-99
Produced exclusively by fission of U-235
Global suppliers:
Kazakhstan, Canada, Australia, Russia, USA
U-235 supplied from france, South Africa, Canada and Argentina
Global Supply of Tc99
Belgium
Netherland
Czech Republic
Poland
Australia
South Africa
Carriers in Radionuclide Preparation
Carrier-free -
only the stated radiotracer is present, without its correspoding nonradioavtive tracer
No-carrier added (NCA)
one where unlabeled tracer or precursor is not added intentionally during radionuclide production (Mo-99 production via fission)
Carrier-added
corresponding nonradioactive tracer is added intentionally (Mo99 production via Mo98 neutron capture)
Specific Activity
The number of disintegrations per unit weight of a sample
mCi/mg
Bq/kg
Ci/g
(carrier-free radionuclide) -shorter half life, less amount of material required to produce given activity= higher SA