Radiology Of Arthritis Flashcards

1
Q

List the most common imaging modalities and what are they for?

A

Radiographs - basic test, trauma, arthritis, congenital, tumour
CT - bone detail, complex fractures
Ultrasound - small superficial lumps, tendons, joints, ligaments and synovitis
Nuclear medicine and PET scanning - cancer staging
MRI - gold standard for assessing diseases of joints, soft tissue and bones
DEXA scanning - osteoporosis
Guided interventional procedures - CT or US guided biopsy, drainage and radio-frequency ablation

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2
Q

Describe the different densities on X-Ray.

A

Bone - white
Air - black
Fat - dark grey
Water (muscle) - grey

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3
Q

Why is it important to take an X-Ray in more than view?

A

An injury may be obscured or not visible from a certain angle
- e.g. Patella fracture can not be seen in an AP/PA view, but it can be seen in a lateral view

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4
Q

Name some different fracture descriptions.

A

Displaced - the two bone edges don’t match up
Angulated - the distal bone isn’t lying flush with the proximal bone
Rotated - the distal bone is twisted
Overriding - the slipping of either part of the fractured bone past the other
Distracted - widening of the gap between the two pieces of fractured bone
Comminuted - a break of splinter in the bone of more than two fragments
Compound - when the broken bone pierces the skin

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5
Q

What is the difference between extra and intra articular fractures?

A

Intra-articular fractures involve the joint space
- these are more serious as they affect the movement of the joint
Extra-articular fractures occur out of the joint space

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6
Q

What are the complications of a supracondylar fracture?

A

Malunion results in ‘gunstock’ deformity due to rotation or inadequate correction of medial collapse
Posterolateral displacement of the distal fragment can damage the neurovascular bundle
- results in neuropraxis that resolves after 3-4 months
- vascular injury results in pulssless, pink hand

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7
Q

Why is fracture of the femoral neck serious?

A

Because the blood supply to the head of the femur, passes through the femoral neck
- can cause an avascular crumbling head

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8
Q

What are the different kind of fractures that can occur around the femoral head?

A
Subcapital neck fracture
Transcervical neck fracture 
Intertrochanteric fracture 
Subtrochanteric fracture 
Fracture of the greater trochanter 
Fracture of the lesser trochanter
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9
Q

Describe Paget’s disease of the bone.

A

Increased bone turnover - osteoclastic and osteoblastic activity
Can be monostotic or polyostotic
Raised alkaline phosphatase
Complications include fractures, deformities and (rarely) sarcomas

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10
Q

Describe the blade of grass sign seen in Paget’s disease.

A

The lucent leading edge of bone seen during the lytic phase of Paget’s disease.

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11
Q

What are the radiological hallmarks of degenerative, inflammatory and depositional arthritis?

A

Degenerative - bone production (sclerosis)
Inflammatory - periarticular erosions
Depositional - periarticular soft tissue masses (e.g. Gout)

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12
Q

Describe the radiological changes seen in reactive bone formation.

A

Sub-chondral sclerosis
Osteophytosis
Periostitis - inflammation of the periosteum

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13
Q

Describe the radiological signs of bone erosion.

A

Location
- peri-articular (occurs at the edge of the joint where the capsule inserts)
- para-articular (near the joint)
Appearance
- if the erosion is ill-defined, the disease is active
- if it is well-defined, the disease is old
Gout erodes further from the joint that RA does

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14
Q

What is the difference in RA and OA regarding the pattern of affected joints?

A

RA - MCP, wrist and PIP joints mainly

OA - DIP and PIP joints mainly

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15
Q

If an inflammatory cause of arthritis is suspected, how can you tell if it is an infection or not?

A

Infections typically only affect on joint at a time

- e.g. RA is a symmetrical polyarthropathy

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16
Q

Briefly describe a primary degenerative arthritis.

A

Excessive wear and tear cause intrinsic degeneration of articular cartilage
Most common in the hips and knees, and least common in the shoulder and elbows

17
Q

What are the X-Ray features of a primary degenerative arthritis?

A

Narrowed joint spaces
Osteophytes
Subchondral sclerosis and cyst formation
In the hand, this appears most commonly in the distal small joints

18
Q

What are some common causes of secondary degenerative arthritis?

A
Trauma 
Infection
Avascular necrosis 
Calcium pyrophosphate dihydrate disease (CPPD)
Rheumatoid arthritis 
Haemophilia
19
Q

Describe secondary degenerative arthritis.

A

Another process that destroys articular cartilage
- degenerative changes supervene
This is different from primary degenerative arthritis because it appears in atypical locations, has an atypical appearance and occurs at an atypical age

20
Q

What are the radiological features of rheumatoid arthritis with secondary degenerative changes?

A

Loss of joint space
Mild articular sclerosis
Lack of osteophytes

21
Q

What is calcium pyrophosphate dihydrate deposition disease?

A

Idiopathic or associated with hyperparathyroidism or haemochromatosis
Symmetrical calcification of articular cartilage
- chondrocalcinosis
- triangular fibrocartilage of the wrist
- common in the knee, hip, symphysis pubis and shoulder
Similar to osteoarthritis - but has a different distribution

22
Q

What are the clinical symptoms of calcium pyrophosphate dihydrate deposition disease?

A

Sudden onset of pain and fever
The joint appears tender, swollen and red
- seems to mimic septic arthritis

23
Q

What are the different types of inflammatory arthritis?

A
Infection
Rheumatoid (seropositive) arthritis 
Seronegative arthopathies 
- psoriatic arthritis 
- reactive arthritis 
- ankylosing spondylitis
- IBD
Connective tissue diseases
- systemic sclerosis 
- systemic lupus erythematosis
24
Q

Describe infective arthritis.

A

More common in adults
Usually caused by local injury (surgery)
Destruction of the cartilage and cortex by infection with staph, strep, TB, etc
Tends to affect one joint (monoarticular)

25
Q

What are the radiological signs of infective arthritis?

A
Soft tissue swelling
Destruction of cartilage and bone
Rapid loss of joint space
With/without periosteal reaction
Osteoporosis
Later subluxation, OA and fusion
26
Q

What are the radiological signs of infective discitis?

A
End-plate erosion 
Disc space narrowing
Bone destruction 
Paravertebral mass
Sclerosis in late disease
Ankylosis
27
Q

Describe the radiological features of rheumatoid arthritis?

A
Hyperaemia 
Soft tissue swelling 
Synovitis 
Effusion 
Bone marrow oedema 
Erosions, cysts
Joint space narrowing 
Secondary degenerative changes
Loose bodies
28
Q

How do seronegative arthropathies differ from RA?

A
Negative rheumatoid factor 
Positive HLA-B27
Normal bone density
Periostitis 
Ankylosis (fusion)
Asymmetrical pattern
29
Q

Describe psoriatic arthritis.

A

More common in men than in women, and occurs most often in young adults
Usually accompanied by skin and nail changes
Seen most often in the DIP joints of the hands and feet
Bone resorption occurs (starting in the distal phalanges)

30
Q

Describe reactive arthritis.

A

More common in men than in women, between the ages of 20-40 and in the caucasian population
Urethritis, arthritis and conjunctivitis
Causes periostitis and enthesopathy, most commonly in the lower limb and sacroiliac joints
Arrives 1-3 weeks after infection (most commonly caused by salmonella, chlamydia and shigella)

31
Q

What is gout?

A

A sodium urate crystal induced synovial inflammation limited to occasional attacks or chronic arthropathy
- crystal deposition induces induces inflammation, enzyme defects or secondary myeloprolifertive disorders

32
Q

Describe the radiological features of gout.

A
Para-articular erosions sharply marinated with sclerotic rims
Overhanging edges 
Joint narrowing occurs later in disease 
Soft tissue swelling
Tophi - not usually calcified 
Common in the 1st MTP joint in the foot