Radiation/Chemotherapy Flashcards
Most common initial symptom of extension of tumor into the brachial plexus vs radiation plexopathy
extension of tumor = pain, involvement of lower trunk.
Radiation plexopathy = numbness and tingling, involvement of upper trunk.
Which chemotherapeutic agents causes pulmonary fibrosis
bleomycin
PNS effects of chemotherapy
Plexopathy or peripheral neuropathy
what parts of the spinal cord is damage in induced transient myelopathy
posterior columns and lateral spinothalamic tract
how long after starting radiation does delayed radiation myelopathy start?
9-18 months
non-surgical radiation used to treat small brain tumors that is very precise and spares injury to rest of brain
sterotactic radiosurgery
EMG findings of peripheral polyneuropathy from radiation
fibrillation potentials and polyphasic MUAPs
most common form of radiation damage
induced transient myelopathy
main difference between induced transient myelopathy and delayed radiation myelopathy
induced is temporary - resolves in 1-9 months.
delayed is irreversible
Pancoast tumor Signs and Symptoms
involvement of lower trunk and Horner’s Syndrome.
Potential bladder complication of chemotherapy
hemorrhagic cystitis
Which chemotherapeutic agents are cardiotoxic
doxorubicin and trastuzumab
Coasting effect
phenomenon seen with platinum-based chemotherapeutics that damages DRG causing progressive sensory polyneuropathy
EMG finding of radiation plexitis
Myokymia
