Radiation Biology Flashcards
Radiation related factors (3)
Absorbed dose
Dose rate
Type and energy
Probability of an effect
No threshold
Stochastic
Severity of injury(NOT probability)
With threshold
Deterministic
Low energy secondary electrons
Delta
Delta rays result in a unique ionization pattern in which closely spaced ionization occurs over a short range along the path of the primary ionization track
Spurs
Longer and less frequent pear shaped tracks
Blobs
Cells are
most sensitive to radiation during
Least sensitive
M phase and the gap bet S phase and mitosis(G2)
During DNA synthesis(S phase)
Temporary hair loss
Occurs at 3weeks(3-6 Gy)
Most radioSENSITIVE(repro)
Spermatogonia
Intermediate follicles
Most radioRESISTANT(repro)
Mature spermatozoa
Small follicles
Radiosensitive(blood)
Lymphocytes
> 12Gy
Gastro syndromes
Greatest sensitivity for rad induced mental retardation
8-15th week
Only organ system that has shown an association bet malformations and low LET radiation doses
CNS