Quizzes Flashcards
When should you perform a UA dip, what four things would make you perform a complete UA?
dip - with presenting urinary sx complete UA - if DIP has: positive: - protein - heme - LE or - nitrate
Early AM voids are best for (4)?
spec gravity
protein
TB
urine cytology
A random SG of greater than 1.020 is a good indication of what? if it’s less than 1.003, what should be suspect?
NO intrinsic KI dz
less than 1.003
KI dz
sickle cell dz
diabetes insipidis
What is optimal urine pH?
- 5
- alkaline urine can indicate renal failure*
what is the only reliable way to quantify proteinuria? what are other methods unreliable?
24 hour urine collection
IF protein loss is greater than 3.5 - nephrotic syndrome, GBM damage
- dip-sticks pick up albumin, not globulin, therefore globulins of Bence-Jones proteins (multiple myeloma pathognomonic) are missed
blood levels have to be greater than what for a dip to respond positive for glucose? what could lead to positive false readings?
170 mg/dl
- glucose will take Na and H2O with it, therefore causing:
polyuria
polydipsia - false positive due to: aspirin, nitrite, XS protein, oxidizing agents
this is useful in detection of asymptomatic urinary tract infections, and may be the only sign of pyelonephritis in women (esp when pregnant), elderly and kiddos. What is it? What is it picking up? And what can create a false positive?
Nitrite
picks up - conversion of nitrate to nitrite via coagulase splitting bacteria (MC e.coli)
false positive
- ascorbic acid
This urinary test is often the first indication of viral hepatitis - what is it/
Urobilinogen
This is seen in:
- increased fat metab with decrease CHO intake
- loss of CHO (vomit, diarrhea)
- inadequate CHO (starvation)
- increased metab (hyperthyroidism, fever)
Ketouria
- ketones are often useful in monitoring diabetics (proper insulin dose)
how do we define, pyuria?
pus in the urine
greater than 5 WBCs/hpf
- if EOS, think drug-induced interstitial nephritis
- TB causes sterile pyuria
When these are present, a specific type can indicate renal tubular damage - what are these, and what are the types (3)?
epithelial cells
- squamous - urethra, vaginal, clue cells*
- renal tubular epithelial - renal tubule, damage!
- transitional - considered normal, unless morphology is odd - cytology if so.
These are hallmark signs of nephrotic syndrome - what are they?
broad, waxy casts
- renal failure casts
These are pathognomonic of acute GN -or vasculitis - what are they?
RBC casts
What is the gold standard for measuring GFR?
inulin infusion
*GFR declines 13 ml/min/decade after the age of 45
This is an accurate and reliable measure of renal function WITHOUT the need for infusion, what is it?
endogenous creatinine clearance
- 24hr urine and serum samples