Quiz 4 Flashcards

1
Q

Patients with single upper tract lesion are at risk of developing bladder carcinoma, the converse is also true?

A

False

  • those with bladder cancer are NOT at increased risk of upper tract lesion
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2
Q

ureteral and renal pelvic cancers have been linked to the following etiologies:

A

smoking
contrast/industrial dyes
NSAID use
BALKAN NEPHROPATHY - along Danube river

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3
Q

Most ureteral (97%) and renal pelvic cancers are . what type?

A

TCC

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4
Q

Patient presents with
gross hematuria
MB flank pain due to ureteral obs and irritative voiding symptoms
You assess them and see an increase in LFTs
- what are you looking at?

A

Ureteral and Renal Pelvic cancer

  • cytology will be positive
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5
Q

What is the most common congenital anomaly of the ureter?

A

Obstruction of the Ureteropelvic Junction

leads to

  • hydronephrosis
  • stones
  • hematuria
  • UTI
  • HTN
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6
Q

this is due to one or both ureters becoming compressed by chronic inflammation in the retroperitoneal tissues - caused by malignant disease, commonly BREAST cancer, Hodgkin’s dz and colon CA. It presents with non-specific symptomology - things like back pn, malaise, anorexia, wt loss and if severe, uremia - what is this?

A

Retroperitoneal fibrosis

  • acquired anomaly of the ureter
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7
Q

this is common in post-menopausal women, it’s often misdiagnosed as a caruncle - what is this? and why does it occur?

A

senile urethritis

  • Low E can cause retrogressive (senile) changes in the vaginal mucosa
  • eversion of mucosa around urethral orifice
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8
Q

this is rare, but will present with slight bleeding on the underwear, generally post-menopausal. When examined - you’ll see benign, red raspberry like, friable vascular tumor that involves the posterior lip of the ext. meatus - what condition is this?

A

urethral caruncle

  • dysuria
  • dyspareunia
  • bloody spotting

BX

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9
Q

this is relatively common in men - they present with decreased urinary stream, spraying, double stream, post-void dribbling - caused by external trauma and or catheterization - what is it?

A

male urethral stricture
ACQUIRED

it’s a fibrotic narrowing of the urethral that is composed of dense collagen and fibroblasts - restricts urine flow and causes dilation of the proximal urethra and prostatic ducts

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10
Q

if a patient presents with
- flank pain, lower abd or testes/labial pn

with potential concomintant sx of
N/V, abd mass, urgency, frequency and polyuria - what would you suspect?

A

hydronephrosis

  • may have HTN from increased renin

Order US

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11
Q

What is newer terminology for Peyronie’s Dz?

A

CITA

Chronic Inflammation of the Tunica Albuginea

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12
Q

up to 10% of men with ED have what?

A

Peyronie’s disease
- plaque on dorsal surface of penis

r/o other causes of:

  • smoking
  • hyperlipidemia
  • HTN
  • DM
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13
Q

patient comes in complaining of penile pain with erection - what is at the top of your differential?

A

Peyronie’s disease

  • wound healing disorder leads to scarring of tunica albiginea
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14
Q

this is a condition where the foreskin cannot be retracted back from the glans penis -

A

phimosis

  • do not force retraction
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15
Q

this is a condition where the foreskin is stuck in the retracted position which could lead to reduced blood flow to the glands and maybe necrosis

A

paraphimosis

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16
Q

this is a term for:

inflammation of the glans penis

A

balanitis

17
Q

this is a term for:

inflammation of the foreskin

A

posthitis

18
Q

this is a term for:

inflammation of both the glans penis and the foreskin

A

balanoposthitis

  • could happen from poor hygiene
19
Q

what is a cause of pathological phimosis and who is found to have it most commonly?

A

balanitis xerotica obliterans (BX)
MC found in middle-aged diabetics
- increased incidence in African American and Hispanic men

20
Q

what percentage of men are circumcised worldwide?

A

30%

  • men who ARE circumcised have almost zero incidence of penile cancer
  • men who are NOT, 2.2/100,000 rate of cancer
21
Q

What strain of HPV is linked to penile cancer?

A

16

22
Q

This condition may cause bloody spotting from the urethra in men - examination may show protruding papilloma

A

condylomata acuminata

23
Q

these occur in up to 30% of men, 1-2mm fleshy or white, dome-shaped papules that arrange themselves circumferentially at the corona - sometimes they are densely packed in several rows - what are these?

A

pearly penile papules

24
Q

Most penile cancers are what?

A

invasive carcinoma of the penis

  • typically originates in the glans
25
Q

what are the three precancerous lesions we need to be aware of?

A
  • leukoplakia - RARE - red, irritated, sore
  • balanitis xerotica obliterans - white patch on prepuse or glans
  • giant condylomata acuminata - cauliflower-like lesion on prepuce, glans or shaft
26
Q

what are the two carcinoma in situ to be aware of?

A

Bowen Disease - red plaque with encrustations

Erythroplasia of Queyrat - VELVETY RED lesions with ulcerations - gen on glans

27
Q

What nodes do the prepuce and shaft skin drain to?

A

superficial inguinal nodes

28
Q

what nodes do the glans and corporal bodies drain to?

A

superficial and deep inguinal nodes

29
Q

Where do the inguinal nodes drain?

A

pelvic nodes

30
Q

Although rare (10% of cases) - where would penile cancer mets to?

A

lung
liver
brain

31
Q

what are the I-IV tumor stages for the penis?

A

I - glans
II - shaft
III - penis and nodes
IV - mets

32
Q

how do you dx penile cancer?

A

biopsy is mandatory

33
Q

what is the prognosis for no-nodal involvement in penile cancer?

A

65-90% 5-year survival

20-50% 5yr for positive inguinal nodes*

Early detection is key and up to 50% of men delay x 1 year before seeking treatment