Quizzes Flashcards

1
Q

6 criteria air pollutants

A
  1. ozone
  2. particulate matter
  3. carbon monoxide
  4. nitrogen oxides
  5. sulfur dioxides
  6. lead
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2
Q

what is a xenobiotic?

A

any substance that is foreign to the body or an entire biological system

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3
Q

the 3 primary routes of absorption are?

A

inhalation
ingestion
dermal absorption

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4
Q

the 3 primary routes of excretion of toxins are?

A

urine
bile
breath

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5
Q

what is the predominant CYP in the liver?

A

3A4

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6
Q

what effect does fasting have on biotransformation?

A

fasting is not a good idea b/c biotransformation requires E that in a fasting state could only be spared at the expense of gluconeogenesis

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7
Q

the EPA sets limits for how much pesticide can remain on food, these limits are known as?

A

MRLs: maximum residue limits

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8
Q

which heavy metal is common in its organic form in shellfish and is one of the reasons you want to have your patients avoid seafood in the wk prior to testing?

A

arsenic

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9
Q

what 2 pollutants combine to form ground level ozone?

A

VOCs + nitrogen oxides

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10
Q

what are the primary causes of acid rain?

A

sulfur dioxide + nitrogen oxides

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11
Q

VOC is an abbreviation for?

A

volatile organic compound

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12
Q

how can we be exposed to VOCs?

A

ingestion
inhalation
topical absorption

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13
Q

the main systems affected by VOCs are?

A

hematologic
nervous
immune

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14
Q

one of the most serious health consequences of exposure to this VOC is leukemia as it basically causes cells to not work effectively, esp those of the BM

A

benzene

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15
Q

this the component of non-stick or Teflon cookware that we are concerned about

A

plytetrafluorethylene (PTFE)

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16
Q

the water-solubility of this toxic substance prevents its access to the lower respiratory tract

A

formaldehyde

17
Q

those who huff glue are mostly after this specific VOC that is 25x more reactive than benzene

A

toluene

18
Q

dry cleaned clothes that are brought home contain elevated levels of this VOC

A

tetrachloroethylene (aka perchloroethylene or PERC)

19
Q

this VOC is a precursor to many medications and is also found as an oral anesthetic ingredient in chloraseptic and carmex

A

phenol

20
Q

the most common VOC that is a potential occupational hazard for persons working in a histology lab and performing tissue processing is

A

xylene

21
Q

what is one major source of the new car smell?

A

vinyl chloride

22
Q

the main ingredient in mothballs is?

A

naphthalene

23
Q

this is a major component of tar from charred/grilled foods and tobacco smoke

A

benzo(a)pyrene

24
Q

what does PAH stand for?

A

polycyclic aromatic hydrocarbon

25
Q

this primary metabolite of nicotine can be used to assess tobacco exposure

A

cotinine

26
Q

this condition is pathognomonic for asbestos exposure

A

mesothelioma

27
Q

these 2 plastics together are considered the safest

A

2 and #4

28
Q

These are used as plasticizers and are of particular concern because they leech very easily

A

phthalates

29
Q

this substance is often found in packaging and in the metal coatings of cans

A

bisphenol A

30
Q

this species is considered “black mold”

A

staphybotrys chartarum

31
Q

what is the major severe health effect of vinyl chloride?

A

hepatic angiosarcoma