Quiz 9: Jaundice, anaemia and polycythaemia Flashcards
What is the definition of jaundice?
An increase in the concentration of bilirubin in the serum.
The yellow discolouration of the skin and sclera due to deposits of bilirubin.
A general feeling of nausea and lethargy.
Yellow skin due to eating carrots.
The yellow discolouration of the skin and sclera due to deposits of bilirubin.
Bilirubin is formed by the breakdown of:
Haemoglobin
Bile
Stercobilin
Proteins
Haemoglobin
What is the normal total serum bilirubin concentration (TSB) in cord blood?
0 µmol/l
Less than 35 µmol/l
35–55 µmol/l
More than 55 µmol/l
Less than 35 µmol/l
Before bilirubin can be excreted by the newborn infant it must first be:
Oxidised in the kidney
Haemolysed in the blood stream
Conjugated in the liver
Digested in the gut
Conjugated in the liver
Jaundice lasting more than 3 weeks after delivery may be caused by:
Hypothyroidism
Hyperthyroidism
Hypoglycaemia
Anaemia
Hypothyroidism
Jaundice is commonest in:
Preterm infants
Term infants
Postterm infants
Underweight for gestational age infants
Preterm infants
Hepatitis commonly presents with obstructive jaundice and:
Dark stools
Pale stools
Blood-stained stools
Blood in the urine
Pale stools
Jaundice between day 2 and 7 is:
Always abnormal
Usually a sign of haemolytic disease
Always treated with phototherapy
Common in normal, healthy infants
Common in normal, healthy infants
Haemolytic disease of the newborn is caused by:
Lack of vitamin K
Bacteria crossing the placenta from the mother to the fetus
A cephalhaematoma or bruising
Damage to fetal red blood cells caused by maternal antibodies
Damage to fetal red blood cells caused by maternal antibodies
ABO haemolytic disease is likely in the following combination of blood groups:
The mother is A and the infant is B.
The mother is A and the infant is O.
The mother is O and the infant is A.
The mother is O and the infant is O.
The mother is O and the infant is A.
A positive Coomb’s test in the cord blood is found in:
Hepatitis
Physiological jaundice
ABO incompatibility
Jaundice of immaturity
ABO incompatibility
Hydrops (generalised oedema of the newborn) is common in:
ABO haemolytic disease
Rhesus haemolytic disease
Biliary atresia
Jaundice of immaturity
Rhesus haemolytic disease
Anti-D immunoglobulin should be given after delivery, miscarriage or antepartum haemorrhage to:
All women
All women who have had a previous infant with Rhesus haemolytic disease
All Rhesus-positive women
All Rhesus-negative women
All Rhesus-negative women
In Rhesus haemolytic disease the mothers blood group may be:
O –ve
O +ve
A +ve
B +ve
O –ve
Rhesus haemolytic disease must be suspected if:
An infant is jaundiced in the first 24 hours of life.
An infant has an elevated haemoglobin.
The Coomb’s test on the cord blood is negative.
The infant is a male.
An infant is jaundiced in the first 24 hours of life.
