Quiz Flashcards

1
Q

hematocrit

A

percentage of total blood volume made of RBCs

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2
Q

if any of what three values are low = anemic

A

RBC, Hgb, Hct

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3
Q

MCV

A

size: macro/micro

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4
Q

MCH

A

hgb weight

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5
Q

MCHC

A

concentration of RBC

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6
Q

anemia due to what 3 things

A

decreased production, increased destruction, blood loss

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7
Q

microcytic hypochromic anemia

A

IDA, ACD, C. blood loss, thalassemia

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8
Q

macrocytic normochromic

A

B12/folic acid deficiency, alcoholism, liver disease

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9
Q

normocytic, normochromic

A

ACD (75%), A. blood loss, hemolytic, aplastic

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10
Q

what is the MC cause of anemia worldwide

A

IDA particularily from GI blood loss due to parasitic infection

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11
Q

MC cause of anemia if post menopausal age (50)

A

GI bleeding due to nonparasitic causes such as ulcer/CA

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12
Q

MC reason of anemia in developed world in pre-menopausal women

A

menses

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13
Q

MC cause of IDA

A

C. blood loss (especially GI tract)

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14
Q

TIBC

A

measures proteins capacity/affinity in the blood that are available to bind with iron

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15
Q

what has increased TIBC

A

IDA and Chronic blood loss

think…if there is no iron…there are a lot of TIBC’s wanting to bing iron. to TIBC increases

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16
Q

what has low TIBC

A

ACD

17
Q

what is ACD

A

inhibition of erythropoesis and altered iron metabolism

18
Q

where is alpha and beta thalassemai seen

A

alpha: china/SE Asia
beta: mediterranean

19
Q

s/s of cooleys/thalassemai major

A

growth failure, bone deformities, marrow expansion, wide diploic space, hair on end, rodent faces, hepatosplenomegaly, jaundice, gallstones

20
Q

what has normal TIBC

A

thalassemia

21
Q

what is done to differentiate alpha/beta thalassemia

A

hemoblobin electrophoresis

22
Q

what does megaloblastic infer

A

inhibition of DNA synthesis in RBC production likely due to folate/B12 deficiency

23
Q

what is the MC cause of B12 deficiency

A

deficiency of IF-pernicious anemia

24
Q

what is the 2/3 MC reasons for B12 deficiency

A

2: lack of gastric acid
3: malabsorption (worm/IBS)

25
Q

s/s of B12 deficiency

A

lemon-yellow skim, premature graying, weakness, sore tongue, GI s/s, paresthesias, loss of vibratory sensation, irritable, emotion instability

26
Q

s/s of megaloblastic

A

glossittis (tonuge) stomatitis (mouth)

27
Q

aplastic anemia

A

normocytic normochromic: decreased RBC, WBC, platlets