Quiz 8

Question 1

Is a metabolic disorder associated with chronic hyperglycemia.

Answer 1

Diabetes Mellitus

Question 2

3ps of Diabetes Mellitus

Answer 2

Polyuria
Polydipsia
Polyhagia

Question 3

Two major hormones that regulate plasma glucose levels

Answer 3

Insulin
Glucagon

Question 4

Metabolic action of Insulin

Answer 4

Glycogenolysis - Decrease
Glucogeneogenesis - Decrease
Everton else - Increase

Question 5

A medical device for determining the approximate glucose level in the blood

Answer 5

Glucometer

Question 6

Finger-stick blood samplers that are used to obtain blood for testing blood sugar (glucose).

Answer 6

Lancet

Question 7

Type of Diabetes where OHA and Insulin therapy is needed

Answer 7

Type 2

Question 8

For insulin injection, The area should be 2-4 inches wide.

Answer 8

False (2-3)

Question 9

For insulin injection, that is at least 2 in. away from the navel. T/F

Answer 9

True

Question 10

When the needle is fully inserted, slowly push down the plunger. Count to ______ and then slowly take the needle out.

Answer 10

Five

Question 11

A diabetogenic substance employed in research. Mechanism : Involves partial degradation of the beta (β) cells of pancreatic islets

Answer 11

Alloxan

Question 12

most frequently used dosage for alloxan

Answer 12

150mg/kg bw

Question 13

Another prominent diabetogenic substance employed in research. a glucosamine–nitrosourea compound that is used clinically as a chemotherapeutic agent in the treatment of pancreatic β cell carcinoma.

Answer 13

Streptozotocin

Question 14

Streptozotocin can induce both type 1 and 2 diabetes mellitus. T/F

Answer 14

True

Question 15

Allocan can induce both type 1 and 2 DM T/F

Answer 15

False (only type 1)

Question 16

Viruses that are associated with type 1 diabetes

Answer 16

Enteroviruses such as:
Coxsackievirus B (CVB)
Rotavirus
Mumps virus
Cytomegalovirus (CMV)

Question 17

Most common enteroviral strain found in pre-diabetic and diabetic individuals.

Answer 17

Coxsackievirus B (CVB)

Question 18

the most common assay used for measurement of insulin antibodies

Answer 18

Radioligand binding (RLB)

Question 19

It increases in plasma levels of glucagon , a lipolytic and hyperglycemic hormone. ü Inhibit insulin secretion

Answer 19

Epinephrine

Question 20

Zinc-chelating agent which causes diabetes in laboratory animals.

Answer 20

Dithizone