QUIZ 5 Part 1

Question 1

responsible for the removal of metabolic
waste and the maintenance of water and
electrolyte balance. Functional unit of the kidney

Answer 1

Nephrons / malphigian bodies

Question 2

tells how healthy the kidney is

Answer 2

Glomerular filtration rate

Question 3

Normal Filtration rate of the body

Answer 3

GFR:125mL/min (180 L/day)

Question 4

Fullfills most of the criteria needed. It is the standard reference in GFR measurement

Answer 4

Inulin

Question 5

Negative about insulin

Answer 5

Time consuming

Question 6

Its clearance is used most extensively. it is the by product of muscle metabolism

Answer 6

Creatinine

Question 7

Reabsorption of water and active secretion of some weak electrolyte ( weak acids)

Answer 7

Active renal secretion

Question 8

Where ACTIVE RENAL SECRETION occurs

Answer 8

proximal Convoluted tubule

Question 9

ACTIVE RENAL SECRETION requires energy and a carrier T/F

Answer 9

True

Question 10

Drugs used to measure active tubular secretion

Answer 10

P-amino hippuric acid (PAH) and iodopyracet (Diodrast)

Question 11

P-amino hippuric acid (PAH) and iodopyracet (Diodrast) are filtered by the glomeruli and secreted by tubular cells T/F

Answer 11

True

Question 12

Where TUBULAR REABSORPTION occurs

Answer 12

Distal convoluted Tubule

Question 13

The reabsorption of drugs that are acids or weak bases is influenced
by?

Answer 13

pH of fluid (urine pH)
pKa of the drug

Question 14

WA + acidic urine=

Answer 14

non-Ionized (reabsorbed)

Question 15

WB + alkaline urine=

Answer 15

non-ionized (reabsorbed)

Question 16

WA + alkaline urine (vice versa)=

Answer 16

ionized (excreted)

Question 17

Measurement of change in concentration of solutes in perfusion
fluid

Answer 17

A. In- vitro Method
Isolated tubule preparation

Question 18

Measurement of urine volume and sodium excretion

Answer 18

In-vivo Method
Lipschitz test

Question 19

Measurement of electrolytes excretion

Answer 19

Saluretic activity

Question 20

Allows localization of tubular site of
action

Answer 20

Micropuncture techniques

Question 21

Amount of filtrate going through the glomerular membrane in one minute

Answer 21

GFR

Question 22

Also known as anti-diuretic hormone

Answer 22

Vasopressin

Question 23

Hormone responsible for RAAS

Answer 23

Renin