Quiz 3

Question 1

What modality of Imaging is used to determine breast density?

Answer 1

Mammogram

Question 2

What two factors are used in the calculation of breast density?

Answer 2

Connective Tissue and Fat

Question 3

What is the significance of Extremely Dense Breast Tissue?

Answer 3

• Difficult to view if its cancer on mammogram
• Makes patient more prone to CA (doubles risk)
• More dense breast higher false negative on mammogram

Question 4

What additional screening is if a women with extremely dense breasts or heterogeneously dense breasts has no additional risk factors?

Answer 4

Just annual Mammography

-No other screening needed

Question 5

What additional screening is needed if a women with extremely dense breasts or heterogeneously dense breasts has additional risk factors?

Answer 5

• Annual Mammography

- Screening MRI

Question 6

What are additional risk factors for CA

Answer 6

• positive family history
• BRCA
• HX of mantle radiation
• atypical hyperplasia
• Menarche
• Age of first live birth
• Breast density!

Question 7

What is the best method of breast imaging in women under age 30?

Answer 7

Sonogram or Ultrasound

Question 8

What is the importance of determining the proximity of biopsy margins from neoplastic tissue?

Answer 8

Clear Margins

Question 9

How are the margins marked for transport to the pathologist?

Answer 9

India Ink

Question 10

What is the significance of atypical hyperplasia on biopsy of a fibrocystic breast mass?

Answer 10

Increases the risk for breast cancer

Question 11

What inhibits beta gluconronidase, which has been associated with increased risk for various CAs, specifically, breast, prostate and colon. Calcium D-glucarate detoxifies chemical carcinogens, steroid hormones and other lipid-soluble toxins, which would otherwise be reabsorbed by beta glucononidase.

Answer 11

Calcium D Glucarate

Question 12

What inhibits tumor growth, by decreasing E receptor

Answer 12

Melatonin

Question 13

decreases 16-hydroxy estrogen CA and shifts the Es to 5-hydroxy estrogen, more protective E.

Answer 13

DIM

Question 14

• oxygen utilization, improves immune function and acts as antioxidant.
• grape seed extract: aromatase inhibitor

Answer 14

CoQ10

Question 15

What is a precursor of ductal carcinoma in situ which is a precourser to cancer, this could make you at risk for future malignancy but it itself is not a malignancy of itself. Diagnosed because it meets some of the criteria of DCIS and it may or may not move to DCIS

Answer 15

A typical Hyperplasia