quiz 3 Flashcards
1
Q
PGI2
A
- vasodilation
- inhibits platelet aggregation
- released from endothelieal cells
- antagonist of TXA2
2
Q
PGD2
A
- increase number of mast cells
- bronchospasm
- decrease hair growth
- allergic reactions
- recruits eosinophils
3
Q
PGE2
A
- vasodilation
- potentiate edema
- fever
- hyperalgia
- uterine contraction/cervix relax for labor
4
Q
PGF2
A
- corpus letum
- luteolysis
- stops production of progesterone
- induces labor
5
Q
TXA2
A
- vasoconstriction
- promotes platelet aggregation
- produced by platlets
- antagonist of PGI2
6
Q
Cyclooxygenase
A
-takes free arachidonic acid and makes prostaglandin G2, then H2
7
Q
phospholipases
A
- creates arachidonic acid
- inhibited by steroids
8
Q
prostaglandin G2
A
- first subset of prostagladins after cyclooxygenase
- vascular component of inflammation
- produced by blood cells
9
Q
5-lipoxygenase
A
takes free arachidonic acid and produces leukotrienes
10
Q
leukotrienes
A
- vasoconstriction
- bronchospasm
- increased permeability
11
Q
Lipoxin
A
- created by 12-lipoxygenase
- vasodilation
- inhibit neutrophil chemotaxis
- stimulate monocyte adhesion
12
Q
vascular component of inflammation
A
- hyperemia
- increased vessel permeability
13
Q
benefits of exudate
A
- dissolution of toxin
- promotion/accumulation antibodies
- stimulation of nociceptors
- promotion of phagocytosis
14
Q
steps of vascular inflammation
A
- vasoconstriction (arteriolar)
- vasodilation of capillary
- exudate pushed out of cell
- blood viscosity increase creating stasis
- increased permeability of vessels increase is osmotic pressure of tissue
15
Q
steps of cellular inflammation
A
- margination (WBC move to vessel edges since RBCs are increasing in size due to clumping)
- rolling
- adhesion(chemical linkage)
- pavementing
- emigration (actively leaves, only in venules, 10 min)
- chemotaxis
- engulfment/destruction
