Quiz 3 Flashcards
what are the 4 key functions of the CNs?
1) motor innervation to muscles of the face, eyes, tongue, jaw, and neck
2) sensory info from skin and muscles of the face and TMJ
3) transmit special sensory info (hearing, vision, smell, vestibular fxns)
4) parasympathetic regulation of pupil size, curvature of lens of eye, HR, BP, breathing, and digestion (3, 7, 9, 10)
what reflexes are mediated by CN 2 (afferent sensory) and 3 (efferent motor)?
pupillary reflex, accomodation reflex, and direct/consensual responses
what is the pupillary reflex?
shine pen light on eyes and the pupils constrict
what is the accomodation reflex?
thickness of the lens changes based on distance of object being focused on
what are direct vs consensual responses?
direct=in the eye being tested
consensual=in the other eye
what are the reflexes mediated by CN 5 (afferent sensory) and CN 7 (efferent motor)?
jaw jerk and corneal
what reflexes are mediated by CN 9 and CN 10?
gag reflex and swallowing reflex
what are the olfactory bulb targets?
pyriform cortex, olfactory tubercle, amygdala, and entorhinal cortex
where does the pyriform cortex go?
orbitofrontal cortex
where do the olfactory tubercle and amygdala go?
orbitofrontal cortex
thalamus
hypothalamus
where does the entorhinal cortex go?
hippocampal formation
where are the olfactory receptors?
in the nose
what is the primary olfactory cortex?
pyriform cortex
the orbitofrontal cortex and thalamus relay what info to each other?
conscious perception of smell
what makes up the secondary cortex?
insula, cingulate cortex, and orbitofrontal cortex
what is responsible for the emotional aspect of smell?
the hypothalamus
what is responsible for the memory of smell and the action afterward?
the hippocampal formation
what does the insula do?
combines taste and smell info
survival functions
perception of flavor
parasympathetic and sympathetic fxns
what would a lesion in the insula result in?
loss of taste and smell
what is the hippocampus responsible for?
hunger
what is the insula/orbitofrontal cortex responsible for?
smell and taste related to addiction (coffee)
what is the amygdala responsible for?
smell influencing hunger
memories related to smell (esp strong emotions)
emotions to food
what are the medial and lateral para-hippocampus responsible for?
quality of smell
sends signal to secondary olfactory area
action related to smell
what is the medial para-hippocampus responsible for?
judgements made based on smell
smell fire, run away
what is the lateral para-hippocampus responsible for?
integrating smell with declarative memory
related to the ability to verbalize what a smell is
what does CN 1 dysfunction result in?
anosmia/hyponosmia
parasmia
olfactory hallucinations
what is anosmia/hyponosmia?
absent/decreased ability to smell
can be temporary, permanent, or progressive
can be congenital or from infection (meningitis/cold)
what would cause permanent anosmia/hyponosmia?
a tumor in the olfactory groove
what is parosmia?
distorted sense of smell, usually unpleasant (something pleasant smells unpleasant)
usually post trauma
what are olfactory hallucinations?
unpleasant smell in the absence of stimuli
what are olfactory hallucinations usually associated with?
insular seizures and epileptic disorders
what can cause olfactory nerve lesions?
TBI-permanent
meningitis-temporary
PD-permanent progressive
Alzheimer’s disease-permanent progressive
Kallmann syndrome
t/f: TBIs often shear nerves in the cribriform plate
true
what is Kallmann syndrome?
genetic condition related to delayed/absent puberty and includes an impaired sense of smell
what is the fxn of CN 2 (optic nerve)?
visual acuity
visual fields
red saturation
what is the somatic motor fxn of CN 3?
levator palpabrae superioris
all extraocular muscles except sup oblique and lat rectus
what is the parasympathetic fxn of CN 3?
pupillary constrictor and ciliary muscles (attached to the lens) for near vision
what is the somatic motor fxn of CN 4?
superior oblique
what is the somatic motor fxn of CN 6 (abducens)?
lateral rectus
what CN makes up the afferent arm of the accomodation reflex?
CN 2
what CN makes up the efferent (motor) arm of the accomodation reflex?
CN 3
what is the fxn of CN 5 (trigeminal)?
innervate muscles of mastication
what are the 3 division of the trigeminal nerve (CN 5)?
V1
V2
V3
what is the V1 division of the trigeminal nerve (CN 5)?
ophthalmic
sensory
forehead
what is the V2 division of the trigeminal nerve (CN 5)?
maxillary
sensory
bw nose and mouth
what is the V3 division of the trigeminal nerve (CN 5)?
mandibular
sensory and motor
mandibles and temporalis
what is the somatosensory fxn of the trigeminal nerve (CN 5)?
afferents for touch , nociceptive, and temp info from the face, ant 2/3 of tongue, anterosuperior external ear, internal ear canal, sinuses, teetch, and meninges
proprioception from the face, TMJ, and tongue
what is the motor fxn of the trigeminal nerve (CN 5)?
efferents to muscles of mastication and tensor tympani muscle
what is the reflex fxn of the trigeminal nerve (CN 5)?
afferent limb corneal reflex
what is trigeminal neuralgia (AKA tic doulourex)?
abrupt onset of severe, sharp, stabbing, electric shock pain in the distribution of one/more branches of the trigeminal nerve lasting less than 2 minutes and can occur several times a day
what branches of the trigeminal nerve (CN 5) are usually involved in trigeminal neuralgia?
V2 or V3, not usually V1
what triggered the symptoms of trigeminal neuralgia?
chewing, talking, brushing teeth, shaving
what are the causes of trigeminal neuralgia?
idiopathic
classic (demyelination)
secondary to trauma, MS, post herpetic neuralgia, or tumor
are more males or females over 50 y/o affected by trigeminal neuralgia?
females
what is the Hallmark disease of the trigeminal nerve?
trigeminal neuralgia
t/f: in severe cases of trigeminal neuralgia, you can have dull aching pain in the absence of an attack
true
if there is a CN 5 lesion, is the direct or consensual response of the corneal (blink) reflex affected?
no direct or consensual responses
if there is a lesion in the spinal trigeminal nucleus, is the direct or consensual response of the corneal (blink) reflex affected?
no direct or consensual responses
if there is a lesion in CN 7, is the direct or consensual response of the corneal (blink) reflex affected?
direct response is lost, but consensual response is in tact if stimulated on the same side as the lesion
direct response is in tact, but consensual response is lost if stimulated on the opposite side of the lesion
what is the stimulus in the corneal (blink) reflex?
cornea is touches and you blink
what CN makes up the afferent (sensory) arm of the corneal (blink) reflex?
CN 5 (trigeminal)
what CN makes up the efferent (motor) arm of the corneal (blink) reflex)?
CN 7 (facial)
what does CN 5 do in the corneal (blink) reflex?
synapses on the interneuron in the spinotrigeminal nucleus in the lateral medulla
trigeminal nerve –> spinal trigeminal nucleus
what does CN 7 do in the corneal (blink) reflex?
facial nerve nucleus–>facial nerve
reflexive closing of the eyelids
ipsilateral response-direct
contralateral response-consensual
what is the direct response?
the response in the ipsilateral eye
what is the consensual response?
the response in the contralateral eye
is there ipsilateral face drooping with a CN 5 or CN 7 lesion?
CN 5 lesion
if there is a CN 7 lesion on the L and the L side is stimulated, what occurs?
no direct response
in tact consensual response
if there is a CN 7 lesion on the L and the R side is stimulated, what occurs?
in tact direct response
no consensual response
if there is a CN 7 lesion on the R and the R side is stimulated, what occurs?
no direct response
in tact consensual response
if there is a CN 7 lesion on the R and the L side is stimulated, what occurs?
in tact direct response
no consensual response
would CN 5 and CN 7 lesions be UMN or LMN lesions?
LMN lesions
would a spinal trigeminal nucleus lesion be an UMN or LMN lesion?
UMN lesion
if there is an UMN lesion, what happens with the corneal (blink) reflex?
no direct or consensual responses
what is one of the most common BS strokes?
lateral medullary lesion
if there is red nucleus, RAS, or cerebellar damage, what happens to the speed and strength of the corneal (blink) reflex?
it is slowed
what is the jaw jerk reflex?
the mandible is tapped just below the lips at the chin while the mouth is held open slightly
is the jaw jerk reflex test performed often? why or why not?
no, bc a (+) response isn’t usually present and can’t tell us what side is affected