Quiz 2 Ruminants Skin and Reproductive

Question 1

what ages does paillomatosis affect most commonly?

Answer 1

yearlings and calves

Question 2

Fibrous core covered with squamous cell epithelium and hyperkeratinization of the outer layers, and vary from:
Small firm to large cauliflowers, grey or black and rough to the touch.

Answer 2

Papillomatosis

Question 3

Where on the body can you find papillomatosis

Answer 3

Teat, udders, head, neck, omasum, vulva, penis, anus

Question 4

Where else does papillomatosis occur?

Answer 4

GI and bladder lesions progressing to squamous cell carcinoma

Question 5

How does papillomatosis enter the body?

Answer 5

Abrasions

Question 6

How do you treat papillomatosis

Answer 6

You dont!! spontaneous regression within 4-6 months.

Question 7

Dx papillomatosis?

Answer 7

Clinical signs.

Question 8

Bovine herpesvirus 2

Answer 8

Bovine mammillitis

Question 9

What are your 2 forms of bovine mammillitis

Answer 9

1 bovine mammillitis

2 pseudolumpyskin

Question 10

Mild fever with skin nodules on face, neck, back and perineum.

The nodules are flat with slightly depressed centers, involving on superficial layers of epidermis which undergo necrosis

Answer 10

Bovine Mammillitis

Question 11

Whats economically important to remember about bovine mammillitis

Answer 11

milk yield can drop 10% and could have concurrent mastitis

Question 12

What are your ddx for pseudolumpyskin?

Answer 12

Warts, cowpox, pseudocowpox, vesicular stomatitis and FMD

Question 13

Control of Bovine Mammillitis

Answer 13

Arthropod transmission is suspected

milking machines need to be kept clean.

Question 14

Parapoxvirus

Poxviridae

Answer 14

Pseudocowpox

Question 15

Where is the world does pseudocowpox occur?

Answer 15

Common endemic Worldwide

Question 16

What are the pathognomonic lesions for pseudocowpox

Answer 16

Horseshoe scabs

Question 17

where on the body will you pseudocowpox?

Answer 17

Teats mainly but also

muzzles and the mouths of suckling calves

Question 18

Bovine Herpesvirus 1

Answer 18

Infectious Pustular vuvlovaginitis and balanoposthitis

Question 19

what spp of cow does ipv occur in?

Answer 19

dairy

Question 20

What do you suspect when you see a cow who is painful to urinate, wide stance, swollen vuvla maybe discharge, and the vestibular mucosa is read with many small pustules

Answer 20

IPV and B

Question 21

Dx of IPV and B

Answer 21

EM
IF of vesicular fluid
PCR

Question 22

Controlling IPV and B?

Answer 22

Eliminate carrier bulls.

Vaccines do not prevent infection, just reduce incidence and severity of disease-DIVA

Question 23

What are your 3 ddx for abortion in cattle?

Answer 23

BVD
IBR
Bluetongue

Question 24

What are prions?

Answer 24

Proteins that have folded incorrectly, and since they are self monoclonal Ab can’t distinguish them

Question 25

What gene is it that mutates?

Answer 25

PrP gene resulting in different conformation, lesions, incubation and mortallity patterns

Question 26

Prions are resistant?

Answer 26

Yes, to heat, UV radiation, and chemicals.

Question 27

How can you reduce the infectivity of a prion?

Answer 27

Autoclaving at 132C for 90min, 1 M NaOH adn phenol extraction

Question 28

How do prions cause spongiform damage and neuronal dysfunction?

Answer 28

They are resistant to endogenous proteases

They accumulate into aggregates called scrapie associated fibrils that form plaques