Quiz 2 Flashcards
What is systemic Lupus Erythematosus
chronic inflammatory tissue disorder
involve multi systems
mostly young women
Body’s production of antibodies against the tissues
Diagnosis of Lupus
Must have 4 of the following:
red malar rash, sensitive to sunlight, joint inflammation, kidney dysfunction, fluid around lungs, LOW WBC, RBC, positive ANA
Symptoms/ clinical manifestations of lupus
unique to the individual
Symptoms/ clinical manifestations of lupus
Drug induced
hydralazine and procainamide (heart and TB meds)
Symptoms/ clinical manifestations of lupus
MSK
arthritis (doesn’t have to be symmetrical
Symptoms/ clinical manifestations of lupus
CNS
headaches, irritable, depression, emotional instability, seizures, cranial neuropathy, CVA
Symptoms/ clinical manifestations of lupus
Integumentary
Digital vasiculitis (brown splinter) malar rash cutaneous lesions discoid lesions (raised red scaling plaques) locatoin on face neck and chest
Symptoms/ clinical manifestations of lupus
Renal
kidney failure
weight gain, edema, HTN
Symptoms/ clinical manifestations of lupus
Systemic
fever, weight gain, malaise, fatigue
PT management for LUPUS
regular exercise (prevent weakness)
avoid sunlight
manage stress
monitor for infection, necrosis, and renal involvement
What is Scleroderma?
Widespread vasculopathy and fibrosis
deposit of collagen in intimate of blood vessels
women > men
Signs and symptoms of Scleroderma
Systemic
Limited skin thickening
distal extremities
widespread rapid progression
overlap w/ LE polymyolitis and dermatomyolitis
Signs and symptoms of Scleroderma
Localized
Single or multiple plaques
w/o skin fibrosis
single or multiple bands
involve skin and deeper tissue
Signs and symptoms of Scleroderma
degenerative changes vascular abnormalities of skin, articular surfaces nondeforming symmetric arthritis interstitial fibrosis esophageal dysfunction hypertension and renal failure cardiac and circulatory disorders, HTN
What are the 3 stages of scleroderma
Edematous stage:
- bilateral nonpitting edema in fingers and hands
Sclerotic stage:
- skin taut, waxy, smooth, seems bound to underlying tissue
Atrophic stage:
- skin atrophy, contractures and ulcers at joints
Sclerodactyly
constrict tendons because of overproduction of collagen
curled and swollen fingers
Signs and symptoms of Scleroderma
CREST
Calcinosis Raynauds phenomemnon (cyanosis, blanched) Esophageal dysmobility Sclerodactyly Telangiectasia
Management of Scleroderma
prevent damage and ulcers wound care avoid excessive bathing Corticosteroids for myolitis Strengthening, ROM, Aquatic therapy Soft tissue will be pressure sensitive
Exercise for patients with Scleroderma
manage based on aerobic capacity
strength and ROM manage based on functional limits
Encourage pt to take BP regularly (prone to HTN)
What is fibromyalgia?
chronic muscle pain syndrome
NOT a disease
associated with hypothyroidism, RA, SLE, and chronic fatigue
mostly in women, not trained athletes
Theoretic etiology of fibromyalgia?
diet, sleep, occupation, seasonal, environment, adverse experiences
Disturbances that occur in fibromyalgia
hypothalamic pituitary adrenal axis (stress system)
ANS (hyperarousal and circulatory)
Reproductive hormone axis
immune system (increased cytokines)
Increased resting muscle tension
Signs and symptoms of fibromyalgia
multiple tender points and muscle pain disturbed sleep w/ morning fatigue and stiffness Aggravation of SX by emotional stress swelling and numbness chronic headaches cold intolerance (raynauds) dysmenorrhea (painful menstration Exercise intolerance Weakness
PT management of Fibromyalgia
local modalities
relaxation techniques, biofeedback, physiologic quieting, soft tissue
Aquatic PT
Gentle graded exercises (NO vigorous exercise)
monitor for overuse
What is Type 1 hypersensitivity
IgE is produced NOT IgG
genetic predisposition
local response to initial encounter
will become systemic
Symptoms / Manifestations of Type 1 Hypersensitivity
hay fever, extrinsic asthma, runny nose, allergic rhinitis
Severe cases = anaphylactic shock
Causes of Type 1 hypersensitivity
pollen, mold, grass, peanuts, shelfish
What is type 2 hypersensitivity
cyotoxic reaction to self antigens
occur in cross reaction b/w exogenous pathogens and endogenous body tissue
Symptoms / Manifestations of Type 2 Hypersensitivity
Strep