Quiz 2 Flashcards
A drug substance administered by any route must possess some
aqueous solubility for systemic absorption and therapeutic response
True
False
Tue
Binds to molecular target (affinity)
Pharmacodynamics
Drug metabolism
Pharmacokinetics
Mechanism of drug action
Pharmacodynamis
Drug distribution
Pharmacokinetics
A drug substance administered by any route must possess some
aqueous solubility for systemic absorption and therapeutic response
True
False
False
It is the science that analyzes how the human body interacts with a drug
and examines how the drug is absorbed, distributed, metabolized, and
excreted by the body
Pharmacodynamics
Pharmacology
Pharmacokinetics
Pharmaceutics
Pharmacokinetics
Deals with the adverse or undesired effects of drugs
Pharmacodynamics
Toxicology
Pharmacokinetics
Pharmacology
Toxicology
Genotoxicity
Mutagenicity study
Detects tumor incidence
Carcinogenic study
Reveals effect of an active ingredient on mammalian reproduction
Reproduction study
Animal studies for a minimum of 2 weeks
Sub-chronic toxicity studt
Animal study perform in a single dat with single dose test
Acute toxicity study
Detects anatomical abnormalities, growth and evelopment
Reproduction study
Animal studies of 90 - 180 days or longer
Sub-chronic toxicity study
Detects mutation or chromosome damage
Mutagenicity study
The primary objective of the animal studies is to obtain basic information
on the drugs effects that maybe safe and effective use in humans
True
False
True
Drug Stability testing at various temperature, conditions of relative
humidity (RH), durations, and environments of light, air and packaging is
essential in assessing drug and drug product integrity
True
False
True
It describes: “what the drug does to the body” *
Pharmacodynamics
The science concerned with drugs, their sources, appearance, chemistry, *1/1
actions and uses. It includes the biochemical and physiologic effects,
mechanism of action, absorption, distribution, biotransformation, and
excretion
Pharmacology
Pharmacokinetics
Pharmacodynamics
Pharmaceutics
Pharmacology