Quiz 2 Flashcards

1
Q

A drug substance administered by any route must possess some
aqueous solubility for systemic absorption and therapeutic response

True
False

A

Tue

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2
Q

Binds to molecular target (affinity)

A

Pharmacodynamics

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3
Q

Drug metabolism

A

Pharmacokinetics

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4
Q

Mechanism of drug action

A

Pharmacodynamis

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5
Q

Drug distribution

A

Pharmacokinetics

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6
Q

A drug substance administered by any route must possess some
aqueous solubility for systemic absorption and therapeutic response

True
False

A

False

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7
Q

It is the science that analyzes how the human body interacts with a drug
and examines how the drug is absorbed, distributed, metabolized, and
excreted by the body

Pharmacodynamics
Pharmacology
Pharmacokinetics
Pharmaceutics

A

Pharmacokinetics

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8
Q

Deals with the adverse or undesired effects of drugs
Pharmacodynamics
Toxicology
Pharmacokinetics
Pharmacology

A

Toxicology

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9
Q

Genotoxicity

A

Mutagenicity study

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10
Q

Detects tumor incidence

A

Carcinogenic study

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11
Q

Reveals effect of an active ingredient on mammalian reproduction

A

Reproduction study

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12
Q

Animal studies for a minimum of 2 weeks

A

Sub-chronic toxicity studt

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13
Q

Animal study perform in a single dat with single dose test

A

Acute toxicity study

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14
Q

Detects anatomical abnormalities, growth and evelopment

A

Reproduction study

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15
Q

Animal studies of 90 - 180 days or longer

A

Sub-chronic toxicity study

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16
Q

Detects mutation or chromosome damage

A

Mutagenicity study

17
Q

The primary objective of the animal studies is to obtain basic information
on the drugs effects that maybe safe and effective use in humans

True
False

A

True

18
Q

Drug Stability testing at various temperature, conditions of relative
humidity (RH), durations, and environments of light, air and packaging is
essential in assessing drug and drug product integrity

True
False

A

True

19
Q

It describes: “what the drug does to the body” *

A

Pharmacodynamics

20
Q

The science concerned with drugs, their sources, appearance, chemistry, *1/1
actions and uses. It includes the biochemical and physiologic effects,
mechanism of action, absorption, distribution, biotransformation, and
excretion

Pharmacology
Pharmacokinetics
Pharmacodynamics
Pharmaceutics

A

Pharmacology