Quiz 2 Flashcards
What are the 3 health surveillance programs and what do they mean?
- resident animal sampling: sampling from animal pop that is being monitored
- soiled bedding sentinels: external animals exposed to soiled bedding from monitored animals, PCR
- environmental sampling: sampling from environment of monitored animals
what are the two main tests for viruses in LAM?
serology, PCR
what are the 3 resp viral pathogens that we have to know?
Sendai virus
Rat Sialodacryoadenitis
Guinea Pig Adenovirus
Sendai virus:
1. who does it affect?
2. main transmission?
3. C/S
- mice!, rats, hamsters
- aerosol, direct contact
- dead neonates, resp signs, chattering
which viruses in LAM are zoonotic?
Lymphocytic choriomeningitis virus
hantavirus
which viruses in LAM are reportable?
rabbit hemorrhagic disease
most viral diseases in LAM result in culling/surveillance… which ones are not included in this?
Sendai virus: self limiting (but cull immunocomp individuals)
Mouse Norovirus: not typically excluded from research colonies
Rat Sialodacryoadenitis:
1. who does it affect?
2. main transmission?
3. C/S
- rats
- aerosol, direct contact
- conjunctivitis, nasal and oral d/c, cervical swellings, resp signs
Guinea pig adenovirus:
1. who does it affect?
2. main transmission?
3. C/S
- guinea pigs
- resp route
- sudden death, resp signs, lethargy, tachypnea
what are the enteric viral pathogens we have to know?
Reovirus, Rotavirus
Reovirus:
1. who does it affect?
2. main transmission?
3. C/S
4. path features?
- mice, rats, hamsters, guinea pigs
- fecal-oral
- abd. distension, oily/matted coat, bright yellow intestinal contents, icterus, tremors, paralysis, death
- bright yellow intestinal contents, hepatomegaly with yellow foci
Rotavirus:
1. who does it affect?
2. main transmission?
3. C/S
4. path features?
- mice, rats, rabbits
- fecal-oral
- intestinal distension, grey-green contents, milk cuddling in stomach, GI signs
- club-shaped intestinal villi
what are the epidermal viral pathogens we need to know?
Mousepox/Extromelia virus
Rabbit pox viruses (myxomatosis, shope fibroma, rabbit pox)
mouse pox/extromelia virus:
1. who does it affect?
2. main transmission?
3. C/S
4. path features?
- mouse
- direct contact
- acute: subclin, ruffled fur, death
chronic: skin lesions, feet + tail necrosis - white foci on spleen and liver, skin ulcers
rabbit pox viruses:
1. who does it affect?
2. main transmission?
3. C/S
- rabbits
- aerosol, arthropods
- masses + ulcers; pox = systemic; shope = self limiting
what are the systemic viral pathogens we have to know?
- Parvovirus
- Lymphocytic choriomeningitis virus
- hantavirus
- mouse hepatitis virus
- Murine adenovirus
- polyomavirus
- mouse norovirus
- theilovirus
- rabbit hemorrhagic disease
Parvovirus:
1. who does it affect?
2. main transmission?
3. C/S
- mice, rats, hamsters
- direct contact
- subclin = most common, dyspnea, ruffled coat, cyanotic scrotum, tooth loss and discolouration, domed cranium
lymphocytic choriomeningitis virus:
1. who does it affect?
2. main transmission?
3. C/S
- mice, hamsters, guinea pigs, non-human primates
- direct contact
- subclin from natural infection, in utero infection = PI –> wasting disease
Hantavirus:
1. who does it affect?
2. main transmission?
3. C/S
- wild rodents
- direct contact, aerosol
- asymptomatic in rodents, humans have systemic disease, resp signs, death
Mouse hepatitis virus:
1. who does it affect?
2. main transmission?
3. C/S
- mice
- direct contact, aerosol
- subclin in immunocompetent, resp + GI signs in young/immunocomp
Murine adenovirus:
1. who does it affect?
2. main transmission?
3. C/S
4. path features?
- mice
- direct contact
- subclinical in immunocompetent, lethargy, wasting, death in immunocomp
- intranuclear inclusion bodies
polyomaivrus:
1. who does it affect?
2. main transmission?
3. C/S
4. path features?
- mice, hamsters
- resp secretions
- tumors, neuro, wasting, trichoepitheliomas in hamsters
- tumors of epithelial and mesenchymal origin
Mouse norovirus:
1. who does it affect?
2. main transmission?
3. C/S
- mice
- fecal-oral
- most subclinical, D+, wasting, death
Theilovirus:
1. who does it affect?
2. main transmission?
3. C/S
4. path features?
- mice, rats
- fecal-oral
- most subclinical, flaccid paralysis
- demyelinating lesions of CNS
Rabbit hemorrhagic disease:
1. who does it affect?
2. main transmission?
3. C/S
- rabbits
- direct contact, excretions, biting insects
- sudden death, neuro and resp signs, hemorrhage
what are the LAM protozoa that we have to know?
- Intestinal coccidiosis (Eimeria spp)
- Hepatic coccidiosis (Eimeria steidae)
- Velvet disease (Piscinoodinium spp)
- White spot disease (ichthyopthirius multifilis)
what are the cestodes we need to know?
Dwarf tapeworm (Hymenolepsis nana)
what are the nematodes we need to know?
- Pinworms (Syphacia spp, Paraspidodera spp)
- Baylisascaris procyonis
- Intestinal capillariasis (Pseudocapillaria tormentosa)
what are the arthropods that we need to know?
- Ascariasis
- Trixacarus caviae
- Chirodiscoides caviae
- Psorptes cuniculi
- Sarcoptes scabei
- Cheyletiella parasitovorax
what are the “other” parasites that we need to know?
- Water molds
- Encephalitozoon cuniculi
Intestinal coccidiosis (Eimeria):
1. who does it affect?
2. main transmission?
3. C/S
- mice, guinea pigs, rabbits (species specific!)
- fecal-oral
- subclin, runting, lethargy, d+
what are the main diagnostics for parasites?
fecal float, PCR, Histo, serology, wet mount of gills/fins, look at intestinal contents to see parasites
what is used to treat arthropod parasites?
ivermectin
how do you treat encephalitozoon cuniculi?
cull or fenbendazole
how do you treat water mold?
salt immersion, cull, fix husbandry
how do you treat nematode parasites?
fenbendazole or cull
how do you treat cestodes?
praziquantel
how do you treat Eimeria spp?
sulfaquinoxaline + evaluate husbandry
how do you treat velvet disease?
prolonged salt immersions, increase H2O temp
how do you treat white spot dz?
salt bath, formalin immersion, increase water temp
Hepatic coccisiosis:
1. who does it affect?
2. main transmission?
3. C/S
4. path findings?
5. blood work findings?
- weanling rabbits
- fecal-oral
- subclin, potbelly, thin, decreased fat reserved, ascites, d+
- hepatomegaly, icterus, circumscribed raised lesions in liver, gall bladder with green bile
- increased serum bilirubin (icterus), decreased fibrinogen
velvet disease:
1. who does it affect?
2. C/S
3. how do you dx?
- zebrafish
- increase mucus prod, skin darkening, surface swimming, flashing, laboured breathing, yellow/rusty sheen in epithelium
- wet mount gills/fin –> grape like clusters of organisms
white spot disease:
1. who does it affect?
2. C/S
3. how do you dx?
- zebrafish
- raised white mucoid nodules, increased mucus prod, laboured breathing
- wet mount –> horseshoe shaped micronucleus
dwarf tapeworm:
1. who does it affect?
2. main transmission?
3. C/S
- mice, rats, hamsters
- fecal-oral
- subclin, weight loss
which parasites are zoonotic?
Dwarf tapeworm
Baylisascaris procyonis
Trixacarus caviae
Cheyletiella parasitovorax
Encephalitozoon cuniculi
pinworms:
1. who does it affect?
2. C/S
- mice, rats, hamsters, guinea pigs, rabbits (species specific!)
- subclin mainly, d+, rectal prolapse, intussusception, fecal impact
Baylisascaris procyonis:
1. who does it affect?
2. C/S
3. path findings?
- guinea pigs, rabbits
- neuro signs
- CNS, heart, liver lesions, granuloma remnants of parasite
intestinal capillariasis:
1. who does it affect?
2. C/S
- zebrafish
- emaciation, darker in color, reduced fecundity, intestinal neoplasms
Ascariasis:
1. who does it affect?
2. C/S
- mice, rats
- pruritis, patchy hair loss, ulceration, pyoderma
Trixacarus caviae:
1. who does it affect?
2. main transmission?
3. C/S
- guinea pigs
- direct contact, fomites
- pruritis, dermatitis, keratosis, crusting, alopecia
Chirodiscoides caviae:
1. who does it affect?
2. main transmission?
3. C/S
- guinea pigs
- direct contact, fomites
- subclinical, pruritis, alopecia, dermatitis
Psorptes cuniculi:
1. who does it affect?
2. C/S
- rabbit (ear mite)
- crusty pruritic ears
Sarcoptes scabei:
1. who does it affect?
2. C/S
- rabbit mange mite
- pruritis, hair loss, crusts, secondary bacterial infection, anemia, leukopenia
Cheyletiella parasitovorax:
1. who does it affect?
2. C/S
- rabbit fur mite
- scaliness, hyperaemia, crusting, hair loss, NOT PRURITIS
water molds:
1. who does it affect?
2. main transmission?
3. C/S
- zebrafish (fish, amphibians, aquatic reptiles)
- motile spores
- injured/immunocompromised –> thin white filaments that build up to puffy, cottony masses
Encephalitozoon cuniculi:
1. who does it affect?
2. main transmission?
3. C/S
- mice, rats, guinea pigs, RABBITS
- direct contact
- subclinical, neuro, uveitis, cataracts