Quiz 2 Flashcards
What are the 3 health surveillance programs and what do they mean?
- resident animal sampling: sampling from animal pop that is being monitored
- soiled bedding sentinels: external animals exposed to soiled bedding from monitored animals, PCR
- environmental sampling: sampling from environment of monitored animals
what are the two main tests for viruses in LAM?
serology, PCR
what are the 3 resp viral pathogens that we have to know?
Sendai virus
Rat Sialodacryoadenitis
Guinea Pig Adenovirus
Sendai virus:
1. who does it affect?
2. main transmission?
3. C/S
- mice!, rats, hamsters
- aerosol, direct contact
- dead neonates, resp signs, chattering
which viruses in LAM are zoonotic?
Lymphocytic choriomeningitis virus
hantavirus
which viruses in LAM are reportable?
rabbit hemorrhagic disease
most viral diseases in LAM result in culling/surveillance… which ones are not included in this?
Sendai virus: self limiting (but cull immunocomp individuals)
Mouse Norovirus: not typically excluded from research colonies
Rat Sialodacryoadenitis:
1. who does it affect?
2. main transmission?
3. C/S
- rats
- aerosol, direct contact
- conjunctivitis, nasal and oral d/c, cervical swellings, resp signs
Guinea pig adenovirus:
1. who does it affect?
2. main transmission?
3. C/S
- guinea pigs
- resp route
- sudden death, resp signs, lethargy, tachypnea
what are the enteric viral pathogens we have to know?
Reovirus, Rotavirus
Reovirus:
1. who does it affect?
2. main transmission?
3. C/S
4. path features?
- mice, rats, hamsters, guinea pigs
- fecal-oral
- abd. distension, oily/matted coat, bright yellow intestinal contents, icterus, tremors, paralysis, death
- bright yellow intestinal contents, hepatomegaly with yellow foci
Rotavirus:
1. who does it affect?
2. main transmission?
3. C/S
4. path features?
- mice, rats, rabbits
- fecal-oral
- intestinal distension, grey-green contents, milk cuddling in stomach, GI signs
- club-shaped intestinal villi
what are the epidermal viral pathogens we need to know?
Mousepox/Extromelia virus
Rabbit pox viruses (myxomatosis, shope fibroma, rabbit pox)
mouse pox/extromelia virus:
1. who does it affect?
2. main transmission?
3. C/S
4. path features?
- mouse
- direct contact
- acute: subclin, ruffled fur, death
chronic: skin lesions, feet + tail necrosis - white foci on spleen and liver, skin ulcers
rabbit pox viruses:
1. who does it affect?
2. main transmission?
3. C/S
- rabbits
- aerosol, arthropods
- masses + ulcers; pox = systemic; shope = self limiting
what are the systemic viral pathogens we have to know?
- Parvovirus
- Lymphocytic choriomeningitis virus
- hantavirus
- mouse hepatitis virus
- Murine adenovirus
- polyomavirus
- mouse norovirus
- theilovirus
- rabbit hemorrhagic disease
Parvovirus:
1. who does it affect?
2. main transmission?
3. C/S
- mice, rats, hamsters
- direct contact
- subclin = most common, dyspnea, ruffled coat, cyanotic scrotum, tooth loss and discolouration, domed cranium
lymphocytic choriomeningitis virus:
1. who does it affect?
2. main transmission?
3. C/S
- mice, hamsters, guinea pigs, non-human primates
- direct contact
- subclin from natural infection, in utero infection = PI –> wasting disease
Hantavirus:
1. who does it affect?
2. main transmission?
3. C/S
- wild rodents
- direct contact, aerosol
- asymptomatic in rodents, humans have systemic disease, resp signs, death
Mouse hepatitis virus:
1. who does it affect?
2. main transmission?
3. C/S
- mice
- direct contact, aerosol
- subclin in immunocompetent, resp + GI signs in young/immunocomp
Murine adenovirus:
1. who does it affect?
2. main transmission?
3. C/S
4. path features?
- mice
- direct contact
- subclinical in immunocompetent, lethargy, wasting, death in immunocomp
- intranuclear inclusion bodies
polyomaivrus:
1. who does it affect?
2. main transmission?
3. C/S
4. path features?
- mice, hamsters
- resp secretions
- tumors, neuro, wasting, trichoepitheliomas in hamsters
- tumors of epithelial and mesenchymal origin