quiz Flashcards
what are the primary lymphoid organs?
foetal liver, bone marrow, thymus
what are secondary lymphoid organs?
spleen, tonsils, lymph node, mucosal lymphoid tissues, smth in intestine
whagt is the function of primary lymphoid organs?
produce store and maturation
what is the function of secondary lymphoid organs
develop, organise and activation
contain B and T cells to help fight diseases
what is the function of the thymus?
select and develop t cell
what does a phagocyte do
engulf and destroy the foreign body.
examples of phagocyte
monocyte, macrophage, dendritic
granulocyte: neutrophils
is a phagocyte under innate or adaptive immunity?
innate
how does B cell kill?
it produces antibodies to fight the pathogen
what is CD4 T cell and what does it do?
it is the T helper cell.
recognise foreign body and bind to antigen presenting cells such as dendritic cells.
Also, it produces cytokines as signals to other cells.
what is CD8 T cell and what does it do?
It is the cytotoxic cell, it kills virus infected or tumour cells.
what is an eosinophil? what does it do? what does it fight against?
it releases active mediators
it is released in response to allergy or asthma
it fight parasites, helminth infections.
what is pathogen associated molecular patterns?
conserved molecular patterns shared by many broad classes.
absent in sterile field.
not shared by host, shared by many pathogens. does not evolve rapidly. targets of innate system
how does macrophages kill ?
phagocytosis+ release reactive oxygen species to damage bacteria
NK cell Natural killer cells how do they kill?
release cytotoxic granules and induce apoptosis
how does B cell kill?
release cytokines and antibodies.
where does B cell develop?
Bone marrow
Where does T cell develop?
thymus, CD4, CD8, CD3
what does B cell expresses?
B cell receptor which secretes antibodies and bind to antigen.
What does B cell fight against?
extracellular infections
what do dendritic cells do?
they are antigen presenting cells. they transport the antigen to the nearest lymph node
dendritic cell prime CD4, CD8 T cell responses.They do this by presenting antigen to the T cells and activating them.
does dendritic cell prime CD4, CD8 T cell responses?
yes
how does dendritic and lymph nodes work together to trigger an immune response?
Dendritic cells are capable of recognizing, taking up, and processing antigens, which are foreign substances such as bacteria and viruses, and presenting them to other cells in the body. This process is known as antigen presentation. Once the dendritic cell has taken up and processed an antigen, it travels to the nearest lymph node, where it presents the antigen to lymphocytes, which are another type of white blood cell. The lymphocytes then respond by producing antibodies, which help the body recognize and fight off the antigen. This is the process by which the body’s immune system is able to recognize and fight off foreign substances.
do dendritic cell kill bacteria?
NO
