Quiz 1 M-Z Flashcards

1
Q

Lithium

A

Blocks PI recycling ?

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2
Q

Lorazepam

A

Enhances GABAergic transmission

Via BZD R

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3
Q

Maprotiline

A

Strongly blocks NE re-uptake

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4
Q

MDMA (Ecstasy)

A

Blocks re-uptake of NE, DA and 5HT

Increase the release ^

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5
Q

Metohexital

A

Barbiturate
Enhances GABA
Short acting
Induction of general anesthesia

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6
Q

Methylphenidate (Ritalin)

A

Inhibit re-uptake of DA and NE

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7
Q

Mianserin

A

Block alpha 2 NE autoreceptor
Raise NE
Anti-depressant

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8
Q

Midazolam

A

Short acting BZD

Enhances GABA-A system

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9
Q

Mirtazepine

A

Blocks NE autoreceptor
Raise NE
Anti-depressant

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10
Q

Moclobamide

A

Blocks MAO-A
Raise NE

Anti-depressant

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11
Q

Muscimol

A

Stimulates GABA-A receptor

Direst agonist

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12
Q

Nipecotic acid

A

Block GABA re-uptake

Renamed tiagabine

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13
Q

Nortriptyline

A

Blocks NE and 5TH re-uptake

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14
Q

Oxazepam

A
Enhances GABA (BZD)
Intermediate half-life
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15
Q

Oxcarbazepine

A

Metabolite blocks VGSC

Anticonvulsant

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16
Q

Paraldehyde

A

Old sedative/hypnotic
Mechanism ?
Use for status epilepsy

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17
Q

Paroxetine (Paxil)

A

SSRI

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18
Q

Penicillin

A

Blocks GABA-A system

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19
Q

Pentobarbital

A

Enhances GABAergic transmission

Via barbiturate receptor

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20
Q

Phenylzine

A

MAOI (non-specific)

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21
Q

Physostigmine (eserine)

A

Blocks acetylcholinesterase

Raise Ach

22
Q

Picrotoxin

A

Blocks GABA-A non-specifically

Via convulsant site

23
Q

Pregabalin

A

Anticonvulsant
Neuropathic pain
Alpha 2 delta subunit of VDCC

24
Q

Progabide

A

Stimulate GABA-A receptor

Direct agonist

25
Q

Propranolol

A

Blocks beta (1 & 2) NE receptor

26
Q

Psudoephedrine

A

Stimulate alpha and beta NE receptors

Decongestant

27
Q

Reserpine

A

Blocks storage of monoamines in vesicles

28
Q

Saclofen

A

Blocks GABA-B receptor

29
Q

Scopolamine

A

Blocks mascarinic receptor

30
Q

Secobarbital

A

Enhances GABAergic transmission

Via barbiturate receptors

31
Q

Sertraline (Zoloft)

A

SSRI

32
Q

Sevoflurane

A

Anesthetic (hypnotic)

Stimulates GABA-A system?

33
Q

Temazepam (Restoril)

A

Stimulate BZD receptor

Hypnotic

34
Q

Tetravenazine

A

Blocks storage of monoamines in vesicles

35
Q

Thiopental

A

Short acting
Stimulate GABAergic transmission
(Via barbiturate receptor )

36
Q

THIP

A

Partial agonist for extra-synaptic GABA-A R

37
Q

Tiagabine

A

Blocks GABA re-uptake

38
Q

TRA 023

A

Non-sedating BZD
Binds Alpha2,3
Enhances GABA

39
Q

Tranylcypromine

A

MAOI (non-selective)

40
Q

Trazodone

A

Antidepressant
Mechanism?
Like an SSRI?

41
Q

Triazolam (halcion)

A

Stimulate BZD R

Hypnotic

42
Q

Trihexyphenidyl

A

Blocks muscarinic receptor

43
Q

Tyramine

A

Cause NE release

Found in food

44
Q

Valproate

A

Mechanism?
Seizures
Depression

45
Q

Venlafaxine

A

SNRI blocks 5HT and NE re-uptake

46
Q

Vigabatrin

A

Blocks GABA metabolism

Block GABA-T

47
Q

Xenon gas

A

Anesthetic

Being tested for anxiety

48
Q

Yohimbine

A

Blocks alpha 2 NE autoreceptor

49
Q

Zaleplon (sonata)

A

Stimulates BZD R?

Hypnotic

50
Q

Zolpidem (ambien)

A

Stimulates BZD R?

Hypnotic

51
Q

Zopiclone (imovane)

A

Stimulates BZD R?

Hypnotic