QUIZ 1: HIGH-RISK PREGNANCY ASSESSMENT AND SCREENING Flashcards
All _____ and deliveries are potentially at risk.
Pregnancies
A ______ is one in which a concurrent disorder, pregnancy-related complication, or external factor jeopardizes the health of the woman, the fetus, or both.
high-risk pregnancy
A _____ is defined as any ascertainable characteristic or circumstance of a person (or group of such persons) known to be associated with an abnormal risk of developing or being adversely affected by a morbid process
risk factor
is a process for defining the nature of that problem, determining a diagnosis, and developing specific treatment recommendations
Assessment
is a process of identifying apparently healthy people who may be at increased risk of a disease or condition.
Screening
is a test to establish the presence (or absence) of disease as a basis for treatment decisions in symptomatic or screen positive individuals (confirmatory test.)
Diagnostic Test
is a test done during pregnancy that uses reflected sound waves to produce a picture of a fetus, the organ that nourishes the fetus (placenta), and the liquid that surrounds the fetus (amniotic fluid).
Fetal ultrasound
It is a technical means of recording (-graphy), the fetal heartbeat (cardio-) and the uterine contractions (-toco-) during pregnancy, typically in the third trimester.
Cartocography
common prenatal test used to check on a baby’s health. During a nonstress test. Also known as fetal heart rate monitoring
Non-stress test
It is performed near the end of pregnancy to determine how well the fetus will cope with the contractions of childbirth.
Contraction Stress Test
small structures in the placenta that act like blood vessels.
Chrionic Villi
These structures contain cells from the developing fetus. A test that removes a sample of these cells through a needle is called
Chorionic Villus Sampling
test that can be done during pregnancy to look for birth defects and genetic problems in the developing baby
Amniocentesis
is most often offered to women who are at increased risk for bearing a child with birth defects.
Amniocentesis
It is the examination of the embryo at 9-10 weeks’ gestation through the intact membranes by introducing an endoscope into the exocoelomic space/cavity transcervically or transabdominally
embryoscopy
is the examination of the fetus after 11 weeks’ gestation. This is performed transabdominally in the amniotic fluid
Fetoscopy
also called percutaneous umbilical cord blood sampling (PUBS), is a diagnostic test that examines blood from the fetus to detect fetal abnormalities
Cordocentesis
A 40-year-old woman with a high body mass index is 10 weeks pregnant. Which diagnostic tool is appropriate to suggest to her at this time?
A. Biophysical profile
B. Amniocentesis
C. Maternal serum alpha-fetoprotein (MSAFP)
D. Transvaginal ultrasound
D. Transvaginal ultrasound
(Transvaginal ultrasound is useful for obese women whose thick abdominal layers cannot be penetrated adequately with the abdominal approach. A biophysical profile is a method of biophysical assessment of fetal well-being in the third trimester. An amniocentesis is performed after the fourteenth week of pregnancy. A MSAFP test is performed from week 15 to week 22 of the gestation (weeks 16 to 18 are ideal). An ultrasound is the method of biophysical assessment of the infant that is performed at this gestational age.)
The nurse is reviewing the contraction stress test (CST) reports of a pregnant patient. The nurse expects the fetus to have meconium-stained amniotic fluid. What would be the reason for that conclusion?
A. Negative CST results
B. Positive CST results
C. Suspicious CST results
D. Unsatisfactory CST results
B. Positive CST results
(Meconium is normally stored in the infant’s intestines until after birth, but sometimes (in cases of fetal distress and hypoxia) it is expelled into the amniotic fluid before birth. The amniotic fluid is then said to be meconium stained. Fewer than three contractions in 10 minutes or late decelerations occurring with 50% or more of contractions constitute positive CST results. Positive CST results are associated with meconium-stained amniotic fluid. Negative CST results indicate that the fetus is normal. Suspicious or unsatisfactory CST results are not associated with any other fetal conditions.)
After reviewing the triple marker screen reports of a patient who is in the second trimester of pregnancy, the nurse concludes that the fetus has trisomy 18. What factors in the report led to the nurse’s conclusion? Select all that apply.
A. Low level of inhibin-A in the maternal serum
B. Low level of unconjugated estriol in serum
C. Elevated nuchal translucency (NT) in the fetus
D. Low level of maternal human chorionic gonadotrophin (hCG)
E. Low level of maternal serum alpha-fetoprotein (MSAFP)
B,D,E
(The triple marker screen measures the levels of three maternal serum markers: unconjugated estriol, hCG, and MSAFP. Low values of unconjugated estriol, hCG, and MSAFP indicate that the fetus has trisomy 18. The quad screen has an additional serum marker: inhibin-A. A low inhibin-A level indicates the possibility of Down syndrome. NT is not a serum marker protein. Moreover, elevated NT indicates that the fetus has a chromosomal abnormality but does not specifically indicate that the fetus has trisomy 18.)
A patient in the first trimester of pregnancy undergoes a triple marker screening test. On reviewing the report, the nurse infers that the fetus may have Down syndrome. What clinical findings are noted by the nurse in the test reports? Select all that apply.
A. High levels of beta-human chorionic gonadotropin (β-hCG)
B. Low levels of pregnancy-associated placental protein (PAPP-A)
C. Low levels of inhibin-A in the fetal blood
D. Low levels of maternal serum alpha-fetoprotein (MSAFP)
E. Low levels of unconjugated estriol in the fetal blood
A,B
(Triple marker screening, which is performed in the first trimester of pregnancy, includes the measurement of two maternal biomarkers: PAPP-A and free β-hCG. High levels of free β-hCG and low levels of PAPP-A in the first trimester indicate that the fetus has Down syndrome, or trisomy 21.Inhibin-A is a placental hormone. Low levels of inhibin-A also indicate the possibility of Down syndrome, but inhibin-A levels are not measured in the triple marker screen; these levels are measured in quad screening. A low level of MSAFP and unconjugated estriol also indicate Down syndrome, but these can be measured only in the second and third trimesters.)
Biochemical examination of the amniotic fluid of a pregnant patient yields the following results: lecithin-to-sphingomyelin (L/S) ratio, 2:1; surfactant-to-albumin (S/A) ratio, 60 mg/g; and phosphatidylglycerol (PG) present. What conclusions will the nurse draw from this report?
A. The fetal lungs are well developed.
B. The gestational age is 36 weeks.
C. The fetus has a neural tube defect.
D. The fetus has an open neural tube defect.
A. The fetal lungs are well developed.
(Biochemical findings such as an L/S ratio of 2:1, an S/A ratio of 60 mg/g, and the presence of PG in amniotic fluid indicate that the fetal lungs are well developed. The gestational age can be predicted only with the help of creatinine and lipid levels in the amniotic fluid. Creatinine levels greater than 2 mg/dL in amniotic fluid indicate that the gestational age is more than 36 weeks. The presence of alpha-fetoprotein (AFP) in the amniotic fluid indicates a neural tube defect in the fetus. The nurse needs to assess AFP levels in the amniotic fluid to determine whether the fetus has an open neural tube defect. A high AFP level in amniotic fluid after 15 weeks’ gestation indicates that the fetus has an open neural tube defect.)
The nurse finds that the nonstress test of a pregnant patient is nonreactive. Which factor in the report might have led the nurse to this finding?
A. No qualifying accelerations in a 20-minute period
B. Two qualifying accelerations in a 20-minute period
C. Less than two qualifying accelerations in a 20-minute period
D. More than two qualifying accelerations in a 20-minute period
C. Less than two qualifying accelerations in a 20-minute period
(The nonstress test is the most widely used technique for prenatal evaluation of the fetus. The results are either nonreactive or reactive. In a nonreactive test, there are less than two qualifying accelerations of the fetal heart rate in a 20-minute period. Absence of fetal heart rate accelerations during the nonstress test indicates that the fetus is sleeping. In a reactive test, there are at least two qualifying accelerations in a 20-minute time period. More than two fetal heart rate accelerations within a 20-minute time period also would be considered a reactive test.)
Nurses should be aware of the strengths and limitations of various biochemical assessments during pregnancy, including that:
A. Chorionic villus sampling (CVS) is becoming more popular because it provides early diagnosis.
B. Screening for maternal serum alpha-fetoprotein (MSAFP) levels is recommended only for women at risk for neural tube defects.
C. Percutaneous umbilical blood sampling (PUBS) is one of the quad-screen tests for Down syndrome.
D. MSAFP is a screening tool only; it identifies candidates for more definitive procedures.
D. MSAFP is a screening tool only; it identifies candidates for more definitive procedures.
(MSAFP is a screening tool, not a diagnostic tool. Further diagnostic testing is indicated after an abnormal MSAFP. CVS does provide a rapid result, but it is declining in popularity because of advances in noninvasive screening techniques. MSAFP screening is recommended for all pregnant women. MSAFP, not PUBS, is part of the quad-screen tests for Down syndrome.)