Quiz 1 drugs (ANS) Flashcards by Spencer Barlow

Q

What is the effect of NE on heart rate, blood pressure and PR?

A

*Note mostly used in OR

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Q

What is the effect of EPI on heart rate, blood pressure and PR?

A

*Note increasing the dose can cause an increase in blood pressure

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Q

What is the effect of Isoproterenol on heart rate, blood pressure and PR?

A

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Q

Which sympathomimetic drug has far higher affinity for alpha receptors than for beta?

A

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Q

Do dobutamine and isoproterenol have a preference for alpha or beta receptors?

A

Beta receptors

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Q

Does isoproterenol or dobutamine have a preference for beta-1 receptors?

A

Dobutamine has a preference for beta-1 receptors (isoproterenol binds beta 1 & 2 roughly equally)

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Q

Can dopamine activate beta and alpha receptors?

A

Yes, at higher doses

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Q

Which G protein is responsible for activating phospholipase C?

A

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Q

Which G protein is responsible for inhibiting adenylyl cyclase?

A

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Q

Which G protein is responsible for stimulating adenylyl cyclase?

A

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Q

How does the acronym “qiss” help with recall of which G protein/2nd messenger system is used with alpha or beta receptors?

A

a1a2b1b2 “q i s s”

alpha-1: Gq -> PLC -> IP3
alpha-2: Gi -> inhibit AC

Beta-1: Gs -> stimulate AC
Beta-2: “

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Q

What G protein/2nd messenger system is associated with M2 receptors? Which is associated with M3 receptors?

A

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Q

What 5 similes are used to describe the symptoms anticholingergic toxicity?

A

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Q

What acronym is used to describe the symptoms of cholinergic toxicity?

A

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Q

A

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Q

What is the MoA of Vasopressin? What is it indicated for?

A

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Q

What is the MoA of Norepinephrine? What is it indicated for? What is a notable side effect?

A

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Q

What is the MoA of Epinephrine? What is it indicated for?

A

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Q

What is the MoA of Phenylephrine? What is it indicated for? What is a notable side effect?

A

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Q

What is the MoA of Oxymetazoline? What is it indicated for?

A

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Q

What is the MoA of Midodrine? What is it indicated for?

A

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Q

What is the MoA of Clonidine? What is it indicated for?

A

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Q

What is the MoA of Methyldopa? What is it indicated for?

A

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Q

What is the MoA of Guanfacine? What is it indicated for?

A

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What is the MoA of Dexmedetomidine? What is it indicated for? What is a notable side effect?

What is the MoA of Brimonidine? What is it indicated for?

What is the MoA of Apraclonidine? What is it indicated for?

What is the MoA of Dobutamine? What is it indicated for?

What is the MoA of Isoproterenol? What is it indicated for?

What is the MoA of Terbutaline? What is it indicated for?

What is the MoA of Albuterol/levalbuterol? What is it indicated for?

What is the MoA of Salmeterol? What is it indicated for?

What is the MoA of Formoterol? What is it indicated for?

What is the MoA of Mirabegron? What is it indicated for?

What is the MoA of Dopamine? What is it indicated for?

What is the MoA of Fenoldopam? What is it indicated for?

What is the MoA of Pseudoephedrine? What is it indicated for?

What is the MoA of Cocaine? What is it indicated for?

What is the MoA of Amphetamine or dextroamphetamine? What is it indicated for?

What is the MoA of Modafinil? What is it indicated for?

What is the MoA of Methylphenidate? What is it indicated for?

What is the MoA of Dexmethylphenidate? What is it indicated for?

What is the MoA of Atomoxetine? What is it indicated for? What is a notable side effect?

What is the MoA of Prazosin? What is it indicated for? What is a notable side effect?

What is the MoA of Terazosin? What is it indicated for? What is a notable side effect?

What is the MoA of Doxazosin? What is it indicated for?

What is the MoA of Tamsulosin? What is it indicated for?

What is the MoA of Phenoxybenzamine? What is it indicated for? What is a notable side effect?

What is the MoA of Phentolamine? What is it indicated for? What is a notable side effect?

What is the MoA of Bisoprolol? What is it indicated for?

What is the MoA of Esmolol? What is it indicated for?

What is the MoA of Atenolol? What is it indicated for?

What is the MoA of Metoprolol? What is it indicated for?

What is the MoA of Propranolol? What is it indicated for?

What is the MoA of Nadolol? What is it indicated for?

What is the MoA of Corteolol? What is it indicated for?

What is the MoA of Timolol? What is it indicated for?

What is the MoA of Sortalol? What is it indicated for?

What is the MoA of Carvedilol? What is it indicated for?

What is the MoA of Labetalol? What is it indicated for?

What is the MoA of Metyrosine? What is it indicated for?

What is the MoA of Acetylcholine? What is it indicated for?

What is the MoA of Methacholine? What is it indicated for?

What is the MoA of Bethanechol? What is it indicated for?

What is the MoA of Cevimeline? What is it indicated for?

What is the MoA of Carbachol? What is it indicated for?

What is the MoA of Pilocarpine? What is it indicated for?

What is the MoA of Edrophonium? What is it indicated for?

What is the MoA of Neostigmine? What is it indicated for?

What is the MoA of Pyridostigmine? What is it indicated for?

What is the MoA of Rivastigmine? What is it indicated for?

What is the MoA of Donepezil? What is it indicated for?

What is the MoA of Galantamine? What is it indicated for?

What is the MoA of Atropine? What is it indicated for?

What is the MoA of Scopolamine? What is it indicated for?

What is the MoA of Dicyclomine? What is it indicated for?

What is the MoA of Tropicamide? What is it indicated for?

What is the MoA of Oxybutynin? What is it indicated for?

What is the MoA of Solifenacin? What is it indicated for?

What is the MoA of Darifenacin? What is it indicated for?

What is the MoA of Tolterodine? What is it indicated for?

What is the MoA of Trospium? What is it indicated for?

What is the MoA of Glycopyrrolate? What is it indicated for?

What is the MoA of Ipratropium? What is it indicated for?

What is the MoA of Tiotropium? What is it indicated for?

What is the MoA of Pralidoxime? What is it indicated for?

What is the MoA of the Botulinum toxin? What is it indicated for?

What effect will Isoproterenol have on HR? On blood pressure (including MAP)? On peripheral resistance?

What effect will NE have on HR? On blood pressure (including MAP)? On peripheral resistance?

What effect will EPI have on HR? On blood pressure (including MAP)? On peripheral resistance?