Quiz 1 drugs (ANS) Flashcards

1
Q

What is the effect of NE on heart rate, blood pressure and PR?

A

*Note mostly used in OR

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2
Q

What is the effect of EPI on heart rate, blood pressure and PR?

A

*Note increasing the dose can cause an increase in blood pressure

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3
Q

What is the effect of Isoproterenol on heart rate, blood pressure and PR?

A
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4
Q

Which sympathomimetic drug has far higher affinity for alpha receptors than for beta?

A
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5
Q

Do dobutamine and isoproterenol have a preference for alpha or beta receptors?

A

Beta receptors

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6
Q

Does isoproterenol or dobutamine have a preference for beta-1 receptors?

A

Dobutamine has a preference for beta-1 receptors (isoproterenol binds beta 1 & 2 roughly equally)

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7
Q

Can dopamine activate beta and alpha receptors?

A

Yes, at higher doses

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8
Q

Which G protein is responsible for activating phospholipase C?

A
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9
Q

Which G protein is responsible for inhibiting adenylyl cyclase?

A
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10
Q

Which G protein is responsible for stimulating adenylyl cyclase?

A
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11
Q

How does the acronym “qiss” help with recall of which G protein/2nd messenger system is used with alpha or beta receptors?

A

a1a2b1b2 “q i s s”

alpha-1: Gq -> PLC -> IP3
alpha-2: Gi -> inhibit AC

Beta-1: Gs -> stimulate AC
Beta-2: “

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12
Q

What G protein/2nd messenger system is associated with M2 receptors? Which is associated with M3 receptors?

A
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13
Q

What 5 similes are used to describe the symptoms anticholingergic toxicity?

A
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14
Q

What acronym is used to describe the symptoms of cholinergic toxicity?

A
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15
Q
A
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16
Q

What is the MoA of Vasopressin? What is it indicated for?

A
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17
Q

What is the MoA of Norepinephrine? What is it indicated for? What is a notable side effect?

A
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18
Q

What is the MoA of Epinephrine? What is it indicated for?

A
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19
Q

What is the MoA of Phenylephrine? What is it indicated for? What is a notable side effect?

A
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20
Q

What is the MoA of Oxymetazoline? What is it indicated for?

A
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21
Q

What is the MoA of Midodrine? What is it indicated for?

A
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22
Q

What is the MoA of Clonidine? What is it indicated for?

A
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23
Q

What is the MoA of Methyldopa? What is it indicated for?

A
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24
Q

What is the MoA of Guanfacine? What is it indicated for?

A
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25
Q

What is the MoA of Dexmedetomidine? What is it indicated for? What is a notable side effect?

A
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26
Q

What is the MoA of Brimonidine? What is it indicated for?

A
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27
Q

What is the MoA of Apraclonidine? What is it indicated for?

A
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28
Q

What is the MoA of Dobutamine? What is it indicated for?

A
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29
Q

What is the MoA of Isoproterenol? What is it indicated for?

A
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30
Q

What is the MoA of Terbutaline? What is it indicated for?

A
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31
Q

What is the MoA of Albuterol/levalbuterol? What is it indicated for?

A
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32
Q

What is the MoA of Salmeterol? What is it indicated for?

A
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33
Q

What is the MoA of Formoterol? What is it indicated for?

A
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34
Q

What is the MoA of Mirabegron? What is it indicated for?

A
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35
Q

What is the MoA of Dopamine? What is it indicated for?

A
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36
Q

What is the MoA of Fenoldopam? What is it indicated for?

A
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37
Q

What is the MoA of Pseudoephedrine? What is it indicated for?

A
38
Q

What is the MoA of Cocaine? What is it indicated for?

A
39
Q

What is the MoA of Amphetamine or dextroamphetamine? What is it indicated for?

A
40
Q

What is the MoA of Modafinil? What is it indicated for?

A
41
Q

What is the MoA of Methylphenidate? What is it indicated for?

A
42
Q

What is the MoA of Dexmethylphenidate? What is it indicated for?

A
43
Q

What is the MoA of Atomoxetine? What is it indicated for? What is a notable side effect?

A
44
Q

What is the MoA of Prazosin? What is it indicated for? What is a notable side effect?

A
45
Q

What is the MoA of Terazosin? What is it indicated for? What is a notable side effect?

A
46
Q

What is the MoA of Doxazosin? What is it indicated for?

A
47
Q

What is the MoA of Tamsulosin? What is it indicated for?

A
48
Q

What is the MoA of Phenoxybenzamine? What is it indicated for? What is a notable side effect?

A
49
Q

What is the MoA of Phentolamine? What is it indicated for? What is a notable side effect?

A
50
Q

What is the MoA of Bisoprolol? What is it indicated for?

A
51
Q

What is the MoA of Esmolol? What is it indicated for?

A
52
Q

What is the MoA of Atenolol? What is it indicated for?

A
53
Q

What is the MoA of Metoprolol? What is it indicated for?

A
54
Q

What is the MoA of Propranolol? What is it indicated for?

A
55
Q

What is the MoA of Nadolol? What is it indicated for?

A
56
Q

What is the MoA of Corteolol? What is it indicated for?

A
57
Q

What is the MoA of Timolol? What is it indicated for?

A
58
Q

What is the MoA of Sortalol? What is it indicated for?

A
59
Q

What is the MoA of Carvedilol? What is it indicated for?

A
60
Q

What is the MoA of Labetalol? What is it indicated for?

A
61
Q

What is the MoA of Metyrosine? What is it indicated for?

A
62
Q

What is the MoA of Acetylcholine? What is it indicated for?

A
63
Q

What is the MoA of Methacholine? What is it indicated for?

A
64
Q

What is the MoA of Bethanechol? What is it indicated for?

A
65
Q

What is the MoA of Cevimeline? What is it indicated for?

A
66
Q

What is the MoA of Carbachol? What is it indicated for?

A
67
Q

What is the MoA of Pilocarpine? What is it indicated for?

A
68
Q

What is the MoA of Edrophonium? What is it indicated for?

A
69
Q

What is the MoA of Neostigmine? What is it indicated for?

A
70
Q

What is the MoA of Pyridostigmine? What is it indicated for?

A
71
Q

What is the MoA of Rivastigmine? What is it indicated for?

A
72
Q

What is the MoA of Donepezil? What is it indicated for?

A
73
Q

What is the MoA of Galantamine? What is it indicated for?

A
74
Q

What is the MoA of Atropine? What is it indicated for?

A
75
Q

What is the MoA of Scopolamine? What is it indicated for?

A
76
Q

What is the MoA of Dicyclomine? What is it indicated for?

A
77
Q

What is the MoA of Tropicamide? What is it indicated for?

A
78
Q

What is the MoA of Oxybutynin? What is it indicated for?

A
79
Q

What is the MoA of Solifenacin? What is it indicated for?

A
80
Q

What is the MoA of Darifenacin? What is it indicated for?

A
81
Q

What is the MoA of Tolterodine? What is it indicated for?

A
82
Q

What is the MoA of Trospium? What is it indicated for?

A
83
Q

What is the MoA of Glycopyrrolate? What is it indicated for?

A
84
Q

What is the MoA of Ipratropium? What is it indicated for?

A
85
Q

What is the MoA of Tiotropium? What is it indicated for?

A
86
Q

What is the MoA of Pralidoxime? What is it indicated for?

A
87
Q

What is the MoA of the Botulinum toxin? What is it indicated for?

A
88
Q

What effect will Isoproterenol have on HR? On blood pressure (including MAP)? On peripheral resistance?

A
89
Q

What effect will NE have on HR? On blood pressure (including MAP)? On peripheral resistance?

A
90
Q

What effect will EPI have on HR? On blood pressure (including MAP)? On peripheral resistance?

A
91
Q
A