Quiz 1 Flashcards
what are the names of disorders caused by ulcers
dumping syndrome, zollinger Ellison syndrome
what does Zollinger-Ellson Syndrom
produces large quantities of gastrin which stimulates HCL attacks the mucosa and causes ulcers on walls on stomach
what is Peptic ulcer disease
ulcerations or erosions in mucosa and submucosa layers of the stomach, duodenum or lower esophagus
what is a common cause of peptic ulcer disease
helicobacter (H) pylori- is a bacteria that can survive in high acidity
what are other causes of peptic ulcer disease
chronic alcohol ingestion, use of NSAIDS
what can you use to treat peptic ulcer
H2 receptor blockers
dumping syndrome
caused by reduction of stomach size
hyperosmolar chime is released into the duodenum too quickly
highly acidic chyme dumped to small intestines
Fluid is drawn from blood reduces blood volume that can cause
hypertension, dizziness, nausea, abdominal pain, hypoglycemia, tachycardia
blood sugar goes up body secretes insulin cuase reduction in glucose
what are the parts of the small intestines
duodenum, jujenum, and ileum
what are the folds called in the small intestines and what do they do
Kerckring, large, circular folds of mucosa, folded into the lumen
villi
finger-like projections
what cells make up villi
enterocytes- they make up the size of the small intestines
microvilli
hair like extensions of cells plasma membranes
what is between the lumen and brush border
unstirred water layer- that is where nutrients has to cross
Crypts of Lieberkuhn
in between villi where mitosis takes place as cell # increase old cell die and fall off intestine cells are rapid turn over cell last 3-5days
Paneth cell
make antimicrobial compound, lysosome (enzyme that destroys bacteria cell wall)
Golblet Cell
secrete large amount of mucus that protect the walls of the intestines
all enzymes in small intestine only work at what pH
7-8
what gland get the body to specific pH and how
brunners gland secretes mucus and small sodium bicarbonate secretions from pancreas rich in sodium bicarbonate which is made in the duodenum
Regulation of intestinal motility and secretions
progressive contractions
segmentation contractions
neural reflexes also affected motility
migrating motility (myoelectric complex
neural reflexes also affect motility
help coordinate motility and secretions from one area to the next