quiz 1 Flashcards
sylvian fissure
appears to be the marker for linguistic capacity
-runs between broca’s and wernicke’s area
angular gyrus
involved in processing of auditory/visual input and language comprehension
-between the parietal, occipital and temporal lobe
angular gyrus integrates, processes and connects functional areas including …..
auditory, visual and language
aphasia
impairment of language that affects the production or comprehension of speech and the ability to read or write
-due to a brain injury (such as a stroke) but can also occur from disorders such as tumors, trauma, infections and MS
wernicke’s aphasia
comprehension of speech is impacted, motor language skills intact
-what they speak is not true speech, it is often nonsense due to lacking feedback comprehension
wernicke’s aphasia has damage to …
wenicke’s area, in the left temporal lobe
-adjacent to the primary auditory area
broca’s aphasia
most language skills are impacted, comprehension is intact
-non-fluent speech, poor repetition, few words and many pauses but aural comprehension is generally intact
broca’s aphasia has damage to …..
broca’s area, in the inferior frontal gyrus of the frontal lobe
-cerebellum may be involved due to it being the internal clock
global aphasia
occurs when a stroke or other condition impacts extensive parts of the front and back regions of the left hemisphere
-significant damage occurs
anomia
specific type of aphasia in which there is difficulty remembering the proper words to describe an attribute, action or object
-results from cortical or subcortical strokes or cerebral insults
executive function
higher level cognitive skills used to control other cognitive abilities and behaviors
-both organizational and regulation abilities
examples of organizational abilities
attention, planning, sequencing, problem solving, working memory and cognitive flexibility
examples of regulation abilities
initiation of action, self control, emotional regulation and decision making
where do executive functions occur
frontal lobe
in particular the prefrontal cortex
what are the 3 divisions of the auditory cortex
primary auditory cortex/core (A1), belt (A2) and the parabelt (A3)
how is spatial processing mediated
it is mediated by two perceptual channels, each with hemifield azimuth tuning with medial borders
-processing near midline depends on the output from both
-spatial processing of sources deep in one or other auditory hemifield is dominated by one or the other channel
how does location of the speech and noise impact how the person perceives the signal
if they are in the same spatial channel it is harder, if they are in different spatial channels it is easier
how do efferent pathways play a role in audition
efferent pathways run from the cortex to the cochlea mediating auditory mechanisms
-in particular the olivocochlear bundle
-carries information from the CANS to the cochlear
-making contact with OHCs affecting their activity
olivocochlear bundle (OCB) in relation to audition
extends from SOC to fibers to cochlear hair cells
-medial OCB is believed to cause OAE suppression
sensitivity
correctly identifying those who have the disorder
- (hit / hit + miss) x 100
specificity
correctly identifying those who do not have the disease
- (correct rejection / correct rejection + false alarms) x 100
stimulus presented, heard it ….
hit
stimulus presented, did not hear it …
miss
no stimulus, heard it ….
false alarm
no stimulus, did not hear it ….
correct rejection
predictive value
the likelihood that a positive result indicates disease or that a negative result excludes disease
-positive PV (PPV) the proportion of positive tests that are true positives
-negative PV (NPV) are the proportion that are negative tests and correct rejections
PPV will be stronger when ……
the disease is more common
ROC curves
a measure of accuracy and meaningful interpretations of test results
-importance in finding the optimal cut off values for normal vs. abnormal test results
within an ROC, there is a diagonal line. what is the function of this
the line is the random guess or chance (50%) performance line
-below the line indicates a not very good test
-above the line indicates a better, more sensitive test
on an ROC, what is plotted on each axis
sensitivity is on the y axis and specificity is on the x axis
what are two pitch perception concepts
frequency discrimination and frequency selectivity
frequency discrimination
ability to detect changes in frequency
frequency selectivity
ability to resolve a complex sound to its component frequencies
theories of pitch perception
place theory and temporal/volley theory
place theory
based around the place of maximum stimulation and tonotopic organization along the basilar membrane
-this corresponds to the maximum displacement in the traveling wave response (frequency place mapping)
what frequencies does the place theory play a larger role with
high frequencies
-believed that phase locking might be necessary for the sensation of pitch
temporal or volley theory (role of auditory neurons)
based on how neurons phase lock to vibrations of the BM and therefore the pitch is assigned to a signal that is determined by the timing pattern of neural impulses evoked by a stimulus
-dependent on the timing
how does the temporal or volley theory work
with neural desynchrony, they fire in a poor pattern leading to not understanding what is being said
-when low frequencies are heard, neurons tend to fire at a particular phase of the waveforms so that the neural spikes are at or close to multiples of the period of pure tones
what is the pitch of missing fundamental
even if the fundamental frequency was removed from the signal, pitch perception did not change which is due to the brain interpreting repetition patterns
how does the pitch of the missing fundamental occur
the first tone that is heard has all the frequencies and the second tone heard has the fundamental removed but maintains all the higher harmonics
-although the character of each note changes, the pitch remains the same
how is pitch perception impacted by a cochlear HL
a cochlear HL is associated with reduced frequency selectivity, meaning a broader auditory filters
-individuals are getting the correct cues
-rely more on temporal information
when there are broader auditory filters or a reduced frequency selectivity, what occurs
speech perception and music appreciation is difficult
why is there variability among people with cochlear HL despite them having similar thresholds
all relating to individual differences in auditory filter size and neural synchrony
-well preserved synchrony is good pitch discrimination