Quinolones Flashcards

1
Q

New Quinolones

A
  1. Ciprofloxacin

2. Ofloxacin

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2
Q

New Fluoroquinolones

A
  1. Levofloxacin

2. Moxifloxacin

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3
Q

Action

A

Bacteriocides - DNA Replication:
Topoisomerase IV
DNA gyrase

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4
Q

Susceptibility 1

A

Gram - : Enterobacteriaceae:

  1. E.coli
  2. Klebsiella
  3. Proteus
  4. Morganella
  5. Salmonella
  6. Shigella
  7. Pseudomonas aeruginosa (+ B-lact)
  8. H. influenza
  9. Brucella
  10. Legionella
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5
Q

Contraindications

A
  1. Children < 16y
  2. Pregnancy
  3. Breast feeding
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