Aminoglycosides Flashcards
1
Q
Names?
A
- Amikacin
- Gentamicin
- Tobramycin
2
Q
Spectrum
A
1. G – bacilli (Mostly !!!) Pseudomonas (Ak > G > T) 2. Mycobacterium Tuberculosis (SM) 3. Protozoa (Paromomycin) 4. Neisseria gonorrheae (Spectinomycin) 5. G + ( only synergism)
3
Q
PK/PD (Pharmacokinetic/Pharmacodynamic)
A
No GI absorption (only IV-IM)
4
Q
Adverse Effects
A
Nephrotoxicity
Ototoxicity