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Antibioticos > QUINOLONAS > Flashcards

QUINOLONAS Flashcards

1
Q

QUINOLONAS, CUALES SON? (5)

A
  1. AC. NALIDIXICO*
  2. NORFLOXACINA*
  3. CIPROFLOXACINA
  4. LEVOFLOXACINA
  5. MOXIFLOXACINA

* YA NO SE USAN

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2
Q

QUINOLONAS, MECANISMO DE ACCION?

A

INHIBEN LA SINTESIS DEL ADN BACTERIANO

ACTUAN SOBRE DNA GIRASA Y TOPOISOMERASA IV

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3
Q

V O F

LAS QUINOLONAS SON TIEMPO DEPENDIENTES

A

F

LAS QUINOLONAS SON CONCENTRACION DEPENDIENTES. NECESITAN DOSIS ALTAS.

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4
Q

QUINOLONAS, FARMACOLOGIA

A
  1. ALTA BIODISPONIBILIDAD ORAL
  2. TODOS NECESITAN CORRECCION PARA FUNCION RENAL EXCEPTO MOXIFLOXACINA
  3. DISTRIBUCION AMPLIA EN LOS TEJIDOS*

*PROSTATA, BILIS, PULMON, NEUTROFILOS Y MACROFAGOS

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5
Q

QUINOLONAS, QUE AFECTA LA BIODISPONIBILIDAD?

QUE NO AFECTA?

A
  1. ALUMINIO
  2. CALCIO
  3. MAGNESIO
  4. SUCRALFATO
  5. MULTIVITAMINICOS CON ZINC

IBP NO AFECTA LA BIODISPONIBILIDAD

ANTIACIDOS QUE CONTENGAN 1,2 Y 3.

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6
Q

CIPROFLOXACINA, ESPECTRO? (3)

A
  1. BGN
  2. PSEUDOMONAS
  3. ATIPICOS
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7
Q

LEVOFLOXACINA, ESPECTRO? (5)

A
  1. PNEUMOCOCO
  2. BGN
  3. PSEUDOMONAS
  4. ATIPICOS
  5. MICOBACTERIAS
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8
Q

MOXIFLOXACINA, ESPECTRO? (5)

A
  1. PNEUMOCOCO
  2. BGN
  3. ANAEROBIOS
  4. ATIPICOS
  5. MICOBACTERIAS
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9
Q

QUINOLONAS RESPIRATORIAS? (2)

A
  1. LEVOFLOXACINA
  2. MOXIFLOXACINA
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10
Q

CIPROFLOXACINA, CUANDO USAMOS?

A

CUANDO QUEREMOS CUBRIR PSEUDOMONAS O BGN

YA NO SE USA PARA GONORREA

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11
Q

LEVOFLOXACINA, CUANDO USAMOS?

A
  1. NEUMONIA
  2. PSEUDOMONAS
  3. BGN
  4. TBC MULTIRESISTENTE
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12
Q

MOXIFLOXACINA, CUANDO USAR?

A
  1. NEUMONIAS
  2. INFECCIONES INTRA-ABDOMINALES
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13
Q

REACCIONES ADVERSAS DE LAS QUINOLONAS? (5)

A
  1. GASTROINTESTINALES
  2. NEUROLOGICOS
  3. ALARGAMIENTO DEL INTERVALO QT
  4. TOXICIDAD MUSCULOESQUELETICA*
  5. ANEURISMA DE AORTA

* RUPTURA DE TENDON DE AQUILES. NO HACER EJERCICIO CUANDO SE USA.

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14
Q

V O F?

QUINOLONAS NO SE PUEDEN USAR EN EL EMBARAZO POR SUS EFECTOS TERATOGENICOS

A

V

RIESGO DE MALFORMACION OSEA FETAL

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Antibioticos (9 decks)

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