QUECTURES

Question 1

What is chromatin?

Answer 1

overall mixture of chromosome and histone protein

Question 2

The 2 sister chromatids in a _____ chromosome are held together by a _____ complex.

Answer 2

metaphase

cohesin

Question 3

Centromere

Answer 3

Part of highly condensed chromosome by the cohesin that is the last part to separate when the chromosome divides

Question 4

2 problems with telomeres

Answer 4

1. free, sticky ends are vulnerable

2. shortening in DNA replication

Question 5

Kinetochore

Answer 5

protein complex that assembles on centromeres where microtubules attach

Question 6

chromosome arms are divided into __(a)_ bands. Top arm is known as the __(b)___ arm, and the bottom arm is known as the __(c)___ arm.

Answer 6

a) cytogenic
b) p arm
c) q arm

Question 7

What can telomeres recruit?

Answer 7

complexes that fold up the ends to prevent damage, such as shelterin

Question 8

What is a karyotype?

Answer 8

chromosomal complement of a cell

Question 9

What is a solenoid?

Answer 9

a coil wound into a tightly packed helix.

Question 10

Down’s syndrome is caused by…

Answer 10

trisomy 21

Question 11

Cri-du-chat syndrome is caused by…

Answer 11

partial deletion of 5th chromosome

Question 12

Fragile X cognitive impairment…

Answer 12

defecttive FMR1 gene on X chromosome