QUANTEC

Question 1

brain

Answer 1

Dmax < 60, necrosis, <3 %

Question 2

brainstem

Answer 2

Dmax < 54, <60 to PRV,

cranial neuropathy or necrosis, <5%

Question 3

optic nerve/chiasm

Answer 3

Dmax < 55, neuropathy, <3%

Question 4

spinal cord

Answer 4

Dmax< 50, myelopathy, 0.2%

Question 5

cochlea

Answer 5

Dmean< 45 Gy, hearing loss, < 30%

Question 6

parotid

Answer 6

mean dose < 25 Gy for combined, < 20 Gy for single

-parotid salivery gland reduced to < 25 %, <20% risk

Question 7

pharynx

Answer 7

Dmean < 50, dysphagia and aspiration, <20%

Question 8

larynx

Answer 8

Dmean<50 Gy, aspiration, <30%

Dmax < 66 Gy, vocal dysfunction, <20%

Question 9

lung

Answer 9

V20Gy < 30% for combined lung, pheumonitis, <20%

mld< 20 Gy, <20%
use mld < 7 Gy Clara

Question 10

esophagus

Answer 10

Dmean<34 Gy, <5-20%, esophagitis

Question 11

heart

Answer 11

Dmean< 26, pericarditis, <15 %

V30Gy< 46 %, <15%

Question 12

liver

Answer 12

Dmean<30Gy, Radiation induced liver disease, <5 %

Question 13

liver SBRT

Answer 13

> 700 cc of normal liver Dmax< 15 Gy, radiation induced liver disease, <5 %

liver - GTV Dmean< 13-18 Gy for 3-6 fractions, <5 %

Question 14

kidney

Answer 14

Dmean< 15-18 Gy, renal dysfunction, <5%
V12<55%
V20<32%
V23<30%
V28<20%, <5%

Question 15

Stomach

Answer 15

D100<45Gy, ulceration, <7%

Question 16

small bowel

Answer 16

V45Gy<195cc, grade 3 acute toxicity, <10%

Question 17

rectum

Answer 17

V50<50%
V60<35%
V65<25%
V70<20%
V75<15%

<15% grade 2 late rectal toxicity
<10% grade 3 late rectal toxicity

Question 18

bladder

Answer 18

Dmax<65
V65<50%
V70<35%
V75<25%
V80<15%

Grade 3 late toxicity, <6%

Question 19

penile bulb

Answer 19

Dmean to 95% og gland <50 Gy, erectile dysfunction, <35%