Qbank Review

Question 1

Translocation of chromosome 15 and 17

Answer 1

Acute promyelocitic leukemia

Question 2

Treatment for translocation of chromosome 15 y 17

Answer 2

All trans retinoic acid
( because it stimulates histone acetylation that promotes maturation and proliferation of granulocytes )

Question 3

Coagulation factores induced by vit K

Answer 3

II, VII, IX, X

Question 4

Translocation of chromosome 14 y 18

Answer 4

Follicular lymphoma

Question 5

Hunger hormone

Answer 5

Ghrelin stimulates the lateral hypothalamus

Question 6

Cause of folicular lymphoma

Answer 6

Mutation of oncogene protein Bcl-2
{that protein is antiapoptopic, inhibits programmed cell death in B lymphocytes}

Question 7

Mutation of FBN1 (fibrilin 1 gene) on chromosome 15

Answer 7

Marfan syndrome

Question 8

Precursor of tyrosine

Answer 8

Phenylalanine

Question 9

Enzyme that converts phenylalanine to tyrosine

Answer 9

Phenylalanine hydroxylase

Question 10

Enzyme deficient in PKU

Answer 10

Phenylalanine hydroxylase

Question 11

Precursors of DOPA (dehydroxyphenylalanine)

Answer 11

Phenylalanine -> tyrosine -> DOPA (dehydroxypenilalaline

Question 12

Enzyme that converts tyrosine to DOPA (dihydroxyphenylalanie)

Answer 12

Tyrosine Hydroxylase

Question 13

Enzyme deficient in albinism

Answer 13

Tyrosinase

Question 14

Enzyme that synthesizes Melanin from DOPA

Answer 14

Tyrosinase

Question 15

Mutation of fibroblast growth factor receptor 3 (FGFR 3)

Answer 15

Achondroplasia

Question 16

Terminal complement deficiency (c5-c9) has increased risk for with pathogen

Answer 16

Neisseria species (N Gonorrhoeae, N Meningiditis)

Question 17

IgA deficiency (selecticve igA, ataxia telangectasia) has increased risk for wich pathogen

Answer 17

Giardia species

Question 18

T-cell immunity (T lymphocyte, CD4,CD8) and IL-17 defects deficiency has increased risk for with pathogen

Answer 18

Fungal infections ( ex Candida)

Question 19

Hyper igM syndrome and significant T cell dysfunction (ex HIV) has increased risk for with pathogen

Answer 19

Pneumocystis species
( ex. P jirovecii, )

Question 20

Decreased interferon gamma and interleukin 12 receptor deficiency has increased risk for with pathogen

Answer 20

Mycobacterium