Pyrexia unknown origin

Question 1

What is the definition of pyrexia of unknown origin?

Answer 1

fever >38.3 >3 weeks with no ID cause

Question 2

What are the four categories of unknown pyrexia?

Answer 2

infective, inflammatory, neoplastic, miscellaneous

Question 3

Give three examples of infection

Answer 3

infective endocarditis 
abdominal abscess 
dental abscess 
chronic sinusitis 
TB
epstein barr virus

Question 4

Three examples of neoplastic causes of PUO?

Answer 4

lymphoma
leukaemia
colon cancer
renal cell carcinoma

Question 5

Three examples of connective tissue PUO causes?

Answer 5

SLE
autoimmune hepatitis
IBD
Sarcoidosis

Question 6

Three examples of ‘miscellaneous’ causes of PUO?

Answer 6

drug fever
PE/DVT
Hyperthyroidism

Question 7

Which test should always be conducted in patients with PUO?

Answer 7

HIV