Purpose Of The Gut Flashcards
Alimentary canal
Mouth Oesophagus Stomach Pancreas Duodenum Jejunum Ileum Cecum Ascending colon Transverse colon Descending colon Sigmoid colon Rectum Anus
Sphincters of oesophagus
Start - upper oesophageal sphincter - prevents air entering GI tract
Bottom - lower oesophageal sphincter - helps prevent reflux into oesophagus from stomach
Stomach function
Storage, physical/ chemical breakdown.
Infection control through HCL
Secretes intrinsic factor to absorb Vit B12 (folate) (without-> pernicious anaemia)
Produces chyme - fluid consist of gastric secretions and partially digested food
Function duodenum
Neutralisation (HCO3) and osmotic stabilisation of chyme (makes less hypertonic)
Bile and pancreatic secretions are delivered into second part through a common entrance for the liver and pancreas
Jejunum and Ileum functions
Final digestion
Nutrient absorption (mainly j)
Water/ electrolyte absorption (mainly I), bile recirculation, B12 absorption (terminal i ) (ileum)
Large bowel function
Final water and electrolyte absorption (Some bile salts and production of some Short chain FAs)
Temporary storage
Autonomic nervous system neurones of sympathetic and parasympathetic
Sympathetic:
CNS -> SHORT preganglionic neurone release Ach -> autonomic ganglia outside CNS -> LONG postganglionic N release mostly noradrenaline -> peripheral effector organs
Parasympathetic:
CNS-> LONG preganglionic neurone releases ACh-> autonomic ganglia-> SHORT postganglionic N release Ach mostly/ neuropeptides (gastric releasing peptide and Vaso-inhibitory peptide) / norepinephrine -> peripheral effector organs (walls of viscera, smooth muscle, endocrine and secretory cells)
Parasympathetic nerves names and supply
Responsible for rest and digest
Originates brain and sacral spine (craniosacral)
Cranial nerves:
3, 7, 9 -> eye, lacrimal gland, sublingual g, submandibular g, mucous membrane of nose and palate, parotid g
10 (vagus Nerve) -> heart (atria muscle fibres, SA/AV nodes, larynx, trachea, bronchi, lungs, liver, gallbladder, bile ducts, stomach, pancreas, colon
Pelvic splanchnic nerves (S2-4) pelvic nerve -> transverse colon- anal canal
Preganglionic and then postganglionic in walls -> myenteric and submucosal plexuses (enteric Ns)
Sympathetic function
Restrict blood flow to viscera and direct it to muscles T1-L2 -> eye, lacrimal g, BVs, salivary, heart, lung, liver, gallbladder, stomach, spleen, AG, kidney, intestines, rectum, genitalia, bladder
T5-L2 innervation to gut
Pass through sympathetic trunk
Splanchnic nerves: synapse on preveterbral ganglia Coeliac, renal, superior mesenteric, inferior mesenteric
Postganglionic go to myenteric and submucosal plexuses (enteric NS)