Purines Flashcards
1
Q
Name 5 purines.
A
IMP GMP AMP guanine adenine
2
Q
What is a base?
A
single or double-ringed structure containing C, O, H, and N
3
Q
What is a sugar?
A
the attachment to the base that may be phosphorylated
4
Q
What is a nucleoside?
A
a base + pentose sugar
5
Q
What is a nucleotide?
A
a phosphorylated sugar + base
6
Q
What is the first product of purine synthesis?
A
IMP
7
Q
Name the key regulated step in activation of the purine sugar.
A
ribose-5-phos. –> PRPP via PRPP synthetase
8
Q
A purine base is made by starting with a ______ and then _____.
A
ribose sugar; building the base on the sugar
9
Q
Name the key regulated step in purine de novo synthesis.
A
PRPP + glu –> 5-phosphoribosylamine via glutamine-phosphoribosyl pyrophosphate aminotransferase
